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  • The electroactivity of DNA was discovered in 1958 by Emil Palecek. Since than, there have been done great progress and development in electrochemistry of nucleic acids at various electrodes. In this review, after brief overview of milestones in research in electrochemistry, history of electroanalysis of DNA follows. Then, the attention is aimed at various electrochemical methods using a mercury electrode as a working one including linear sweep and cyclic polarography/voltammetry (elimination polarography/voltammetry), differential pulse polarography/voltammetry, square wave polarography/voltammetry, AC polarography/voltammetry and chronopotentiometry for analysis of DNA. Coupling of adsorptive transfer stripping technique to the above-mentioned methods is very promising for nucleic acid studying and is discussed. Further, advantages of mercury and amalgam electrodes are mentioned. The advantages of coupling of electroanalysis of DNA at mercury electrodes with paramagnetic particles based isolation of
  • The electroactivity of DNA was discovered in 1958 by Emil Palecek. Since than, there have been done great progress and development in electrochemistry of nucleic acids at various electrodes. In this review, after brief overview of milestones in research in electrochemistry, history of electroanalysis of DNA follows. Then, the attention is aimed at various electrochemical methods using a mercury electrode as a working one including linear sweep and cyclic polarography/voltammetry (elimination polarography/voltammetry), differential pulse polarography/voltammetry, square wave polarography/voltammetry, AC polarography/voltammetry and chronopotentiometry for analysis of DNA. Coupling of adsorptive transfer stripping technique to the above-mentioned methods is very promising for nucleic acid studying and is discussed. Further, advantages of mercury and amalgam electrodes are mentioned. The advantages of coupling of electroanalysis of DNA at mercury electrodes with paramagnetic particles based isolation of (en)
Title
  • Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review
  • Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review (en)
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  • Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review
  • Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review (en)
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  • RIV/00216305:26620/11:PU93025!RIV14-MSM-26620___
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  • P(ED1.1.00/02.0068), P(KAN208130801)
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  • 4
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  • 184770
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  • RIV/00216305:26620/11:PU93025
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  • DNA, mercury electrode, DNA hybridization, nucleic acid, reduction of nucleobases, genosensors, biosensors, nanomaterials, magnetic beads, nanotechnology, automation (en)
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  • NL - Nizozemsko
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  • [CE453A68ABDC]
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  • Current Physical Chemistry
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  • 1
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  • Adam, Vojtěch
  • Chomoucká, Jana
  • Hubálek, Jaromír
  • Hynek, David
  • Kizek, René
  • Prášek, Jan
  • Trnková, Libuše
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  • 1877-9476
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  • 26620
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