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  • Doxorubicin is a planar aromatic molecule and it is commonly used in cancer chemotherapy. In this study, we compared nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation when the aluminium layer was transformed to the porous alumina layer. Then gold material was deposited into the pores. After removal of aluminium template the nanostructured surface made of ordered gold nanocolumns on metal underlay was obtained. Flat gold electrodes were fabricated by evaporation of gold layer to the silicon substrate. After that, all electrodes were characterized by electrochemical impedance spectroscopy and then the detection of doxorubicin was studied by differential pulse voltammetry. According to the impedance spectroscopy measurements a bigger electroactive area for nanostructured electrodes was proved. The gold nanocolumns have been found as a significant factor in increasing of e
  • Doxorubicin is a planar aromatic molecule and it is commonly used in cancer chemotherapy. In this study, we compared nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation when the aluminium layer was transformed to the porous alumina layer. Then gold material was deposited into the pores. After removal of aluminium template the nanostructured surface made of ordered gold nanocolumns on metal underlay was obtained. Flat gold electrodes were fabricated by evaporation of gold layer to the silicon substrate. After that, all electrodes were characterized by electrochemical impedance spectroscopy and then the detection of doxorubicin was studied by differential pulse voltammetry. According to the impedance spectroscopy measurements a bigger electroactive area for nanostructured electrodes was proved. The gold nanocolumns have been found as a significant factor in increasing of e (en)
Title
  • Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements
  • Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements (en)
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  • Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements
  • Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements (en)
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  • RIV/00216305:26220/13:PU105471!RIV14-GA0-26220___
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  • P(ED2.1.00/03.0072), P(GAP102/11/1068)
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  • 66217
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  • RIV/00216305:26220/13:PU105471
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  • gold nanocolumns, impedance spectroscopy, differential pulse voltammetry, doxorubicin (en)
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  • [551749947173]
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  • Drbohlavová, Jana
  • Hubálek, Jaromír
  • Hrdý, Radim
  • Prášek, Jan
  • Kynclová, Hana
  • Přibyl, Jakub
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  • 26220
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