About: Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • The pH-rate profile of the pseudo-first-order rate constants for the rearrangement and hydrolysis of Ezetimibe giving (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-3-carboxamide (2) as the main product at pH of less than 12.5 and the mixture of 2 and 5-(4-fluorophenyl)-5-hydroxy-2-[(4-fluorophenylamino)-(4-hydroxyphenyl)methyl]-pentanoic acid (3) at pH of more than 12.5 in aqueous tertiary amine buffers and in sodium hydroxide solutions at ionic strength I = 0.1 mol L-1 (KCl) and at 39 degrees C is reported.
  • The pH-rate profile of the pseudo-first-order rate constants for the rearrangement and hydrolysis of Ezetimibe giving (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-3-carboxamide (2) as the main product at pH of less than 12.5 and the mixture of 2 and 5-(4-fluorophenyl)-5-hydroxy-2-[(4-fluorophenylamino)-(4-hydroxyphenyl)methyl]-pentanoic acid (3) at pH of more than 12.5 in aqueous tertiary amine buffers and in sodium hydroxide solutions at ionic strength I = 0.1 mol L-1 (KCl) and at 39 degrees C is reported. (en)
Title
  • Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe
  • Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe (en)
skos:prefLabel
  • Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe
  • Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe (en)
skos:notation
  • RIV/00216275:25310/14:39897721!RIV15-MSM-25310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, S
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 24246
http://linked.open...ai/riv/idVysledku
  • RIV/00216275:25310/14:39897721
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ezetimibe.; Hydrolysis; Rearrangement; Catalysis; Mechanism; Kinetics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [0037FB5B22FC]
http://linked.open...i/riv/nazevZdroje
  • Journal of Pharmaceutical Science
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 103
http://linked.open...iv/tvurceVysledku
  • Imramovský, Aleš
  • Hájíček, Josef
  • Hanusek, Jiří
  • Baťová, Jana
  • Hejtmánková, Ludmila
http://linked.open...ain/vavai/riv/wos
  • 000340277700003
issn
  • 0022-3549
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/jps.24070
http://localhost/t...ganizacniJednotka
  • 25310
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 97 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software