About: Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones     Goto   Sponge   NotDistinct   Permalink

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Description
  • A new method for the synthesis of substituted 5-(2-hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4- ones and 5-(2-hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones is described, starting from phenylthioureas and 3-bromotetrahydrofuran-2-one. The reaction proceeds under mild conditions, is very simple to perform, and is applicable to a relatively wide range of substituents in benzene nucleus. Some 1,3-thiazolidin-4-ones show dynamic NMR behavior in solution because of prototropy tautomerism and E/Z-stereoisomerism.
  • A new method for the synthesis of substituted 5-(2-hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4- ones and 5-(2-hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones is described, starting from phenylthioureas and 3-bromotetrahydrofuran-2-one. The reaction proceeds under mild conditions, is very simple to perform, and is applicable to a relatively wide range of substituents in benzene nucleus. Some 1,3-thiazolidin-4-ones show dynamic NMR behavior in solution because of prototropy tautomerism and E/Z-stereoisomerism. (en)
Title
  • Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones
  • Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones (en)
skos:prefLabel
  • Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones
  • Efficient Synthesis of 5-(2-Hydroxyethyl)-2-phenylimino-1,3-thiazolidin-4-ones and 5-(2-Hydroxyethyl)-2-phenylamino-4,5-dihydro-1,3-thiazol-4-ones (en)
skos:notation
  • RIV/00216275:25310/09:00008315!RIV10-MSM-25310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021627501)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
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  • 312524
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  • RIV/00216275:25310/09:00008315
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • ring transformation; thiazole; synthesis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [E61537A989E9]
http://linked.open...i/riv/nazevZdroje
  • Journal of Heterocyclic Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 46
http://linked.open...iv/tvurceVysledku
  • Růžička, Aleš
  • Váňa, Jiří
  • Sedlák, Miloš
  • Hanusek, Jiří
http://linked.open...n/vavai/riv/zamer
issn
  • 0022-152X
number of pages
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  • 25310
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