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| - Abstract Objective: Information concerning un-supplemented plasma concentrations of ubiquinol-10 in coronary artery disease patients is still controversial. The aim of this study is to determine the levels of plasma ubiquinol-10 and ratios of ubiquinol-10 to plasma lipids in consecutive patients with different angiographic findings. Subjects and methods: Thirty-six consecutive patients who underwent coronary angiography were split in two groups with different atherosclerotic changes. These patients were un-supplemented with antioxidants and were not treated by lipid-lowering medication. We have measured a plasma level of ubiquinol-10 using high-performance liquid chromatography with coulometric detection. Conventional plasma lipids, markers of oxidative stress and other widely accepted risk factors of atherosclerosis have been determined too. Results: Plasma ubiquinol-10 to low-density lipoprotein cholesterol (LDL-C) ratios in patients with different angiographic findings have been found out a
- Abstract Objective: Information concerning un-supplemented plasma concentrations of ubiquinol-10 in coronary artery disease patients is still controversial. The aim of this study is to determine the levels of plasma ubiquinol-10 and ratios of ubiquinol-10 to plasma lipids in consecutive patients with different angiographic findings. Subjects and methods: Thirty-six consecutive patients who underwent coronary angiography were split in two groups with different atherosclerotic changes. These patients were un-supplemented with antioxidants and were not treated by lipid-lowering medication. We have measured a plasma level of ubiquinol-10 using high-performance liquid chromatography with coulometric detection. Conventional plasma lipids, markers of oxidative stress and other widely accepted risk factors of atherosclerosis have been determined too. Results: Plasma ubiquinol-10 to low-density lipoprotein cholesterol (LDL-C) ratios in patients with different angiographic findings have been found out a (en)
- Úvod: Informace o plazmatických hladinách ubichinolu-10 u pacientů s kardiovaskulárními onemocněními jsou stále rozporuplné. Cílem této studie bylo stanovit hladiny ubichinolu-10 v plazmě a poměry ubichinolu-10 ku plasmatickým lipidům u konsekutivních pacientů s rozdílnými koronarografickými nálezy. Subjekty a metody: Třicet-šest konsekutivních pacientů, kteří podstoupili koronarografii, bylo rozděleno do dvou skupin podle různého stupně atherosklerotických změn. Tito pacienti nebyli suplementováni antioxidanty a nebyli léčeni hypolipidemiky. Plazmatickou hladinu ubichinolu-10 jsme měřili pomocí vysoce účinné kapalinové chromatografie s coulometrickou detekcí. Dále byly stanoveny hladiny plazmatických lipidů, markerů oxidačního stresu a dalších obecně uznávaných rizikových faktorů aterosklerózy. Výsledky: Hladiny ubichinolu-10 v plazmě a poměry k LDL-C u pacientů s rozdílnými koronarografickými nálezy byly 180+/-69 a 132+/-43 (p = 0,020). Poměr ubichinol-10/LDL-C byl významně nižší u koronarografi (cs)
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Title
| - Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings
- Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings (en)
- Poměry ubichinol-10/lipidy u konsekutivních pacientů s různými koronarografickými nálezy (cs)
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skos:prefLabel
| - Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings
- Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings (en)
- Poměry ubichinol-10/lipidy u konsekutivních pacientů s různými koronarografickými nálezy (cs)
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skos:notation
| - RIV/00216275:25310/07:00006159!RIV08-MSM-25310___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...ai/riv/idVysledku
| - RIV/00216275:25310/07:00006159
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Coenzyme Q10; Ubiquinol-10; Lipoperoxidation; Atherosclerosis; Coronary artery disease; Coronary angiography; HPLC; Coulometric detection (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kanďár, Roman
- Skalický, Jiří
- Škarydová, Lucie
- Žáková, Pavla
- Vojtíšek, Petr
- Myjavec, Andrej
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http://linked.open...n/vavai/riv/zamer
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