About: Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects

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About: Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://link.springer.com/article/10.1007%2Fs11910-014-0491-3
Description	The resting brain exhibits continuous intrinsic activity, which is correlated between groups of regions forming resting state networks. Evaluating resting connectivity is a popular approach for studying brain diseases. Several hundred studies are now available that address integrity of resting connectivity in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI), as well as preclinical at-risk subjects. Most studies focus on the default mode network, a system of specific brain areas showing strong connected resting activity that attenuates during goal-directed behavior. The extent of intrinsic brain activity tends to be strongly correlated with cognitive processes and is specifically disrupted in AD and MCI patients and at-risk subjects, with changes seeming to evolve during the transition between the disease stages. The resting brain exhibits continuous intrinsic activity, which is correlated between groups of regions forming resting state networks. Evaluating resting connectivity is a popular approach for studying brain diseases. Several hundred studies are now available that address integrity of resting connectivity in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI), as well as preclinical at-risk subjects. Most studies focus on the default mode network, a system of specific brain areas showing strong connected resting activity that attenuates during goal-directed behavior. The extent of intrinsic brain activity tends to be strongly correlated with cognitive processes and is specifically disrupted in AD and MCI patients and at-risk subjects, with changes seeming to evolve during the transition between the disease stages. (en)
Title	Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects (en)
skos:prefLabel	Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects (en)
skos:notation	RIV/00216224:14740/14:00074325!RIV15-MSM-14740___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GA14-33143S)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	11773
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/14:00074325
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Functional connectivity; fMRI; Resting state; Resting state networks; Default mode network; Alzheimer's disease; Mild cognitive impairment (en)
http://linked.open.../riv/klicoveSlovo	Resting state Resting state networks Default mode network Functional connectivity Alzheimer's disease fMRI Mild cognitive impairment
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[483C98E3BFA3]
http://linked.open...i/riv/nazevZdroje	CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Vliv fyziologických procesů na reliabilitu a časovou proměnlivost konektivity v lidském mozku měřené pomocí fMRI
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	14
http://linked.open...iv/tvurceVysledku	Rektorová, Irena Mikl, Michal Mareček, Radek Krajčovičová, Lenka
http://linked.open...ain/vavai/riv/wos	000342073900008
issn	1528-4042
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s11910-014-0491-3
http://localhost/t...ganizacniJednotka	14740

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