About: DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease     Goto   Sponge   NotDistinct   Permalink

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Description
  • The DBS STN is a non-curative treatment; its effect on the patient's quality of life (QoL) determines the therapeutic success of this procedure. We aimed to assess whether stimulation parameters setting may influence also some of the non-motor aspects of QoL. The QoL was assessed by PDQ-39 questionnaire. The questionnaire was administered to patients before and after the DBS surgery. A sham change of stimulation amplitude was performed before the actual increase. After the further amplitude increase in subgroup of patients (mean increase of amplitude of 0.35 V), there was a statistically significant additional improvement of total PDQ-39 score by another 22.9 %. In this group the emotions, stigma and communication subscales improved after the stimulation increase, without further change of UPDRS III.
  • The DBS STN is a non-curative treatment; its effect on the patient's quality of life (QoL) determines the therapeutic success of this procedure. We aimed to assess whether stimulation parameters setting may influence also some of the non-motor aspects of QoL. The QoL was assessed by PDQ-39 questionnaire. The questionnaire was administered to patients before and after the DBS surgery. A sham change of stimulation amplitude was performed before the actual increase. After the further amplitude increase in subgroup of patients (mean increase of amplitude of 0.35 V), there was a statistically significant additional improvement of total PDQ-39 score by another 22.9 %. In this group the emotions, stigma and communication subscales improved after the stimulation increase, without further change of UPDRS III. (en)
Title
  • DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease
  • DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease (en)
skos:prefLabel
  • DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease
  • DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease (en)
skos:notation
  • RIV/00216224:14740/13:00070577!RIV14-MSM-14740___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED1.1.00/02.0068)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 68022
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14740/13:00070577
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Deep brain stimulation (DBS); Subthalamic nucleus (STN); Non-motor symptoms; Quality of life (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • AT - Rakouská republika
http://linked.open...ontrolniKodProRIV
  • [68859A123ABC]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neural Transmission
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 120
http://linked.open...iv/tvurceVysledku
  • Baláž, Marek
  • Rektor, Ivan
  • Bočková, Martina
http://linked.open...ain/vavai/riv/wos
  • 000317076600022
issn
  • 0300-9564
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00702-013-0990-4
http://localhost/t...ganizacniJednotka
  • 14740
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