About: Protein engineering of beta-D-mannosidase     Goto   Sponge   NotDistinct   Permalink

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  • N-Acetyl-D-mannosamine (ManNAc) is often used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. ManNAc is also a synthetic intermediate for a number of carbohydrate-derived families of biologically active compounds and pharmaceutical candidates. For this reason ManNAc is of keen interest to scientists around the world. The main goal of this work, because no N-Acetyl-mannosaminidase has been identified in the nature, is to produce N-acetyl-mannosaminidase via mutagenesis of beta-D-mannosidase and to apply this new enzyme in possible enzymatic synthesis of structures containing ManNAc.
  • N-Acetyl-D-mannosamine (ManNAc) is often used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. ManNAc is also a synthetic intermediate for a number of carbohydrate-derived families of biologically active compounds and pharmaceutical candidates. For this reason ManNAc is of keen interest to scientists around the world. The main goal of this work, because no N-Acetyl-mannosaminidase has been identified in the nature, is to produce N-acetyl-mannosaminidase via mutagenesis of beta-D-mannosidase and to apply this new enzyme in possible enzymatic synthesis of structures containing ManNAc. (en)
Title
  • Protein engineering of beta-D-mannosidase
  • Protein engineering of beta-D-mannosidase (en)
skos:prefLabel
  • Protein engineering of beta-D-mannosidase
  • Protein engineering of beta-D-mannosidase (en)
skos:notation
  • RIV/00216224:14740/13:00066122!RIV14-GA0-14740___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • P(GAP207/10/0321)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 100523
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  • RIV/00216224:14740/13:00066122
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  • protein engineering mannosidase mutation affinity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [8CBA74204318]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Demo, Gabriel
  • Wimmerová, Michaela
  • Weignerova, Lenka
  • Fliedrova, Barbora
http://localhost/t...ganizacniJednotka
  • 14740
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