About: Speeding up MS imaging with fast mirror scanning

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	High resolution mass spectrometry imaging (MSI) analysis may involve mass spectra recording from 10 000 or more measurement points. Though a new generation of mass spectrometers with kHz lasers brought significant decrease of MSI time, one image acquisition can still consume many hours. In such a device utilizing high repetition laser the total imaging time is no longer limited only by the data acquisition but also by the speed of the target stage translation. With a proper design of ion source optics, speeding up of the MSI can be achieved by substitution of the stage translation with a fast scanning mirror redirecting the desorption laser beam in micrometer scale. A prototype with 2 kHz 355 nm Nd:YAG laser and the fast precision scanning mirror was used to record 10 000 pixel MS map with 100 acquisitions per pixel in 12,5 minutes, an order of magnitude faster compared to the commercial instrument, 1 kHz AutoFlexTM Speed (Bruker Daltonics). High resolution mass spectrometry imaging (MSI) analysis may involve mass spectra recording from 10 000 or more measurement points. Though a new generation of mass spectrometers with kHz lasers brought significant decrease of MSI time, one image acquisition can still consume many hours. In such a device utilizing high repetition laser the total imaging time is no longer limited only by the data acquisition but also by the speed of the target stage translation. With a proper design of ion source optics, speeding up of the MSI can be achieved by substitution of the stage translation with a fast scanning mirror redirecting the desorption laser beam in micrometer scale. A prototype with 2 kHz 355 nm Nd:YAG laser and the fast precision scanning mirror was used to record 10 000 pixel MS map with 100 acquisitions per pixel in 12,5 minutes, an order of magnitude faster compared to the commercial instrument, 1 kHz AutoFlexTM Speed (Bruker Daltonics). (en)
Title	Speeding up MS imaging with fast mirror scanning Speeding up MS imaging with fast mirror scanning (en)
skos:prefLabel	Speeding up MS imaging with fast mirror scanning Speeding up MS imaging with fast mirror scanning (en)
skos:notation	RIV/00216224:14740/12:00057870!RIV13-GA0-14740___
http://linked.open...avai/predkladatel	Středoevropský technologický institut
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GCP206/10/J012), S
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Tomalová, Iva Bednařík, Antonín Kuba, Pavel
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	170395
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/12:00057870
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mass spectrometry imaging; MALDI TOF MSI (en)
http://linked.open.../riv/klicoveSlovo	mass spectrometry imaging MALDI TOF MSI
http://linked.open...ontrolniKodProRIV	[AB667B9D1227]
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Analysis of Biomolecules with Nanomaterials Assisted Laser Desorption/Ionization Mass Spectrometry
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Preisler, Jan Tomalová, Iva Houška, Pavel Bednařík, Antonín Moskovets, Eugene Kuba, Pavel
http://localhost/t...ganizacniJednotka	14740

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