About: New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The p53 tumour suppressor protein is a nuclear phosphoprotein which plays a key role in cell cycle regulation. One of the critical issues of p53 response to cellular stress or DNA damage is the way of its activation. It has been suggested that posttranslational modification involving phosphorylation of p53 protein is most likely the mechanism through which the activity of p53 protein may be regulated. Recently, it has been also shown that phosphorylation of Ser392 is important for p53-mediated transcriptional activation in vivo. Preparation of the monoclonal antibodies that are specific to either phosphorylated or unphosphorylated epitopes within the target protein provides a powerful technique for studying the role of p53. The p53 tumour suppressor protein is a nuclear phosphoprotein which plays a key role in cell cycle regulation. One of the critical issues of p53 response to cellular stress or DNA damage is the way of its activation. It has been suggested that posttranslational modification involving phosphorylation of p53 protein is most likely the mechanism through which the activity of p53 protein may be regulated. Recently, it has been also shown that phosphorylation of Ser392 is important for p53-mediated transcriptional activation in vivo. Preparation of the monoclonal antibodies that are specific to either phosphorylated or unphosphorylated epitopes within the target protein provides a powerful technique for studying the role of p53. (en)
Title	New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 (en)
skos:prefLabel	New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 (en)
skos:notation	RIV/00216224:14330/01:00004152!RIV/2002/GA0/143302/N
http://linked.open.../vavai/riv/strany	148
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA301/00/P094), P(GA312/99/1550), P(NI4703)
http://linked.open...iv/cisloPeriodika	47
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Vojtěšek, Bořivoj Kaňková, Kateřina Nenutil, Rudolf
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Fakulta informatiky
http://linked.open...dnocenehoVysledku	688773
http://linked.open...ai/riv/idVysledku	RIV/00216224:14330/01:00004152
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392 (en)
http://linked.open.../riv/klicoveSlovo	New Monoclonal Antibodies Recognizing p53 Protein Phosphorylated by Casein Kinase II at Serine 392
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[8BBAC720BD99]
http://linked.open...i/riv/nazevZdroje	Folia Biologica
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	The study of mechanisms regulating the activity of p53 protein and the possibilities of its latent forms activation in cancer cell The role of p53, p73 and IRF-1 proteins in regulation of the cell response do DNA damage Immunoregulatory defects in patients with humoral immunodeficiencies
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	2001
http://linked.open...iv/tvurceVysledku	Pospíšilová, Šárka Vojtěšek, Bořivoj Kaňková, Kateřina Svitáková, Miluše Nenutil, Rudolf
issn	0015-5500
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	14330

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software