About: The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia     Goto   Sponge   NotDistinct   Permalink

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  • Eighty percent of children with AML show clonal chromosomal aberrations on cytogenetic examination. The most frequent aberrations rexognised in AML are t(8;21), t(15;17), inv(16) and 11q23. These aberrations comprise 10-45% of all AML cases in choldren. Recently, the molecular genetic examination of these specific changes is available with the sensitivity of finding one leukemic cell bearing the translocation in between 1 million of normal cells.
  • Eighty percent of children with AML show clonal chromosomal aberrations on cytogenetic examination. The most frequent aberrations rexognised in AML are t(8;21), t(15;17), inv(16) and 11q23. These aberrations comprise 10-45% of all AML cases in choldren. Recently, the molecular genetic examination of these specific changes is available with the sensitivity of finding one leukemic cell bearing the translocation in between 1 million of normal cells. (en)
  • Eighty percent of children with AML show clonal chromosomal aberrations on cytogenetic examination. The most frequent aberrations rexognised in AML are t(8;21), t(15;17), inv(16) and 11q23. These aberrations comprise 10-45% of all AML cases in choldren. Recently, the molecular genetic examination of these specific changes is available with the sensitivity of finding one leukemic cell bearing the translocation in between 1 million of normal cells. (cs)
Title
  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia
  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia (en)
  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia (cs)
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  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia
  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia (en)
  • The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia (cs)
skos:notation
  • RIV/00216224:14310/99:00001441!RIV09-MZ0-14310___
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  • 734444
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  • RIV/00216224:14310/99:00001441
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  • acute myeloid leukemia (en)
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  • [2B8A11510F90]
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  • Michálek, Jaroslav
  • Šmarda, Jan
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  • Czechoslovak Biological Society
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  • 80-7232-069-6
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  • 14310
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