About: Mybs in mouse hair follicle development

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/journal/00408166
Description	The Myb transcription factors are involved in essential cellular processes, such as cell proliferation, dif-ferentiation and cell death. Biological functions carried out by specific Myb proteins are distinct. Hairfollicles are ectodermal-derived organs with cycling character of the growth resulting from the pres-ence of somatic stem cells. In this study, we followed the expression of the Myb proteins in developinghair follicles and in the hair follicle stem cell niche by immunofluorescence staining. During hair follicledevelopment, B-Myb was present in a few cells located in the area of cell division; c-Myb was abun-dant postanally in dividing cells but also in keratinizing zone. In addition, c-Myb was also detected incells under the hair follicle bulge. These findings indicate possible involvement of c-Myb in regulation of activated stem cells leaving the niche. The Myb transcription factors are involved in essential cellular processes, such as cell proliferation, dif-ferentiation and cell death. Biological functions carried out by specific Myb proteins are distinct. Hairfollicles are ectodermal-derived organs with cycling character of the growth resulting from the pres-ence of somatic stem cells. In this study, we followed the expression of the Myb proteins in developinghair follicles and in the hair follicle stem cell niche by immunofluorescence staining. During hair follicledevelopment, B-Myb was present in a few cells located in the area of cell division; c-Myb was abun-dant postanally in dividing cells but also in keratinizing zone. In addition, c-Myb was also detected incells under the hair follicle bulge. These findings indicate possible involvement of c-Myb in regulation of activated stem cells leaving the niche. (en)
Title	Mybs in mouse hair follicle development Mybs in mouse hair follicle development (en)
skos:prefLabel	Mybs in mouse hair follicle development Mybs in mouse hair follicle development (en)
skos:notation	RIV/00216224:14310/14:00076373!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(EE2.3.20.0183), P(GAP502/12/1285), P(GCP302/12/J059), S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Veselá, Barbora Šmarda, Jan Švandová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	31250
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00076373
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mybs; hair follicles; development; stem cells (en)
http://linked.open.../riv/klicoveSlovo	stem cells development Mybs hair follicles
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[38DDD1330855]
http://linked.open...i/riv/nazevZdroje	Tissue and Cell
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Apoptotic and non-apoptotic functions of caspases in hard tissue formation Center of Experimental Biomedicine Cellular and molecular mechanisms in tooth-bone complex formation
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	46
http://linked.open...iv/tvurceVysledku	Šmarda, Jan Matalová, Eva Veselá, Barbora Švandová, Eva
http://linked.open...ain/vavai/riv/wos	000343808600009
issn	0040-8166
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.tice.2014.06.006
http://localhost/t...ganizacniJednotka	14310

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