About: Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling

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About: Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Mass spectrometry (MS) of complex biomolecules is mostly performed using Matrix-Assisted Laser Desorption Ionization (MALDI) with Time of Flight (TOF) detection. Development of nanotechnology and nanomaterials (NMs) and nanoparticles (NPs) with their unique physical and chemical properties brought to MS alternative media for efficient ionization of analytes and accelerated development of Surface-Assisted Laser Desorption Ionization (SALDI), Surface-Enhanced Laser Desorption Ionization (SELDI) and Nano-Assisted Laser Desorption Ionization (NALDI). These techniques contributed significantly to MS [1]. NMs possess also extensive applications in MALDI TOF MS tissue imaging in current nanomedicine [2]. In this work, we studied applications of various NMs (either as matrices or surfaces) in MS analysis of histological tissue sections. We also evaluated effect of NMs on the ionization of various peptides and the comparison with common organic matrices was done. Mass spectrometry (MS) of complex biomolecules is mostly performed using Matrix-Assisted Laser Desorption Ionization (MALDI) with Time of Flight (TOF) detection. Development of nanotechnology and nanomaterials (NMs) and nanoparticles (NPs) with their unique physical and chemical properties brought to MS alternative media for efficient ionization of analytes and accelerated development of Surface-Assisted Laser Desorption Ionization (SALDI), Surface-Enhanced Laser Desorption Ionization (SELDI) and Nano-Assisted Laser Desorption Ionization (NALDI). These techniques contributed significantly to MS [1]. NMs possess also extensive applications in MALDI TOF MS tissue imaging in current nanomedicine [2]. In this work, we studied applications of various NMs (either as matrices or surfaces) in MS analysis of histological tissue sections. We also evaluated effect of NMs on the ionization of various peptides and the comparison with common organic matrices was done. (en)
Title	Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling (en)
skos:prefLabel	Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling Use of nanomaterials for TOF mass spectrometry of complex biomolecules and for tissue profiling (en)
skos:notation	RIV/00216224:14310/14:00075127!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED2.1.00/03.0086), Z(MSM0021622411)
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kolářová, Lenka Havel, Josef Hampl, Aleš Vaňhara, Petr
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	52316
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00075127
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MALDI MS; Nanotechnology; Nanoparticles; Nanoflowers; Tissue profiling (en)
http://linked.open.../riv/klicoveSlovo	Tissue profiling Nanoparticles MALDI MS Nanotechnology Nanoflowers
http://linked.open...ontrolniKodProRIV	[63C61AC4123C]
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional R&D center for low-cost plasma and nanotechnology surface modifications
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Havel, Josef Hampl, Aleš Kolářová, Lenka Vaňhara, Petr Salvado, Victoria Puig Romero, Mireia
http://linked.open...n/vavai/riv/zamer	Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface
http://localhost/t...ganizacniJednotka	14310

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