About: Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Exposure to particulate matter (PM) in ambient air has been shown to lead to adverse health consequences. Six size fractions of PM with aerodynamic diameter smaller than 10 mu m (PM10) and gas phase were collected at six localities with different major pollution sources. Extracts of samples were assessed for AhR-mediated toxicity, (anti-)estrogenicity, (anti-)androgenicity and genotoxicity. The biological responses were interpreted relative to chemical characterization. Historically, for regulatory purposes, evaluation of air pollution was based mainly on assessment of the sum of PM10. In the case of AhR-mediated activity, PM1 was responsible for more than 75% of the activity of the particulate fraction from all localities. The assessed effects were correlated with concentrations of polycyclic aromatic hydrocarbons (PAH), organic carbon content and specific surface area of the PM. A significant proportion of biologically active chemicals seems to be present in the gas phase of air. Exposure to particulate matter (PM) in ambient air has been shown to lead to adverse health consequences. Six size fractions of PM with aerodynamic diameter smaller than 10 mu m (PM10) and gas phase were collected at six localities with different major pollution sources. Extracts of samples were assessed for AhR-mediated toxicity, (anti-)estrogenicity, (anti-)androgenicity and genotoxicity. The biological responses were interpreted relative to chemical characterization. Historically, for regulatory purposes, evaluation of air pollution was based mainly on assessment of the sum of PM10. In the case of AhR-mediated activity, PM1 was responsible for more than 75% of the activity of the particulate fraction from all localities. The assessed effects were correlated with concentrations of polycyclic aromatic hydrocarbons (PAH), organic carbon content and specific surface area of the PM. A significant proportion of biologically active chemicals seems to be present in the gas phase of air. (en)
Title	Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies (en)
skos:prefLabel	Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies (en)
skos:notation	RIV/00216224:14310/14:00073576!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED0001/01/01), P(GPP503/10/P249), S
http://linked.open...iv/cisloPeriodika	february
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Novák, Jiří Klánová, Jana Čupr, Pavel Hilscherová, Klára Landlová, Linda Kohút, Lukáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	8413
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00073576
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PM size fractions; Dioxin-like toxicity; Estrogenicity; Antiandrogenicity; Genotoxicity (en)
http://linked.open.../riv/klicoveSlovo	Estrogenicity Antiandrogenicity Dioxin-like toxicity Genotoxicity PM size fractions
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[481E5FF3C2CF]
http://linked.open...i/riv/nazevZdroje	Environment International
http://linked.open...in/vavai/riv/obor	DI
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	CETOCOEN Assessment of multiple biological effects of air pollutants mixtures in vitro
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	63
http://linked.open...iv/tvurceVysledku	Hilscherová, Klára Klánová, Jana Novák, Jiří Čupr, Pavel Landlová, Linda Kohút, Lukáš Giesy, John P
http://linked.open...ain/vavai/riv/wos	000330909900008
issn	0160-4120
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.envint.2013.10.013
http://localhost/t...ganizacniJednotka	14310

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