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  • This study focuses on mapping the life cycle of Cryptosporidium muris in two laboratory rodents; BALB/c mice and the southern multimammate rat Mastomys coucha, differing in their prepatent and patent periods. Both rodents were simultaneously experimentally inoculated with viable oocysts of C. muris (strain TS03). Animals were dissected and screened for the presence of the parasite using a combined morphological approach and nested PCR (SSU rRNA) at different times after inoculation. The occurrence of first developmental stages of C. muris in stomach was detected at 2.5 DPI. The presence of Type II merogony, appearing 36 hours later than Type I merogony, was confirmed in both rodents. Oocysts exhibiting different size and thickness of their wall were observed from 5 DPI onwards in stomach of both host models. The early phase of parasitisation in BALB/c mice progressed rapidly, with a prepatent period of 7.5–10 days; whereas in M. coucha, the developmental stages of C.
  • This study focuses on mapping the life cycle of Cryptosporidium muris in two laboratory rodents; BALB/c mice and the southern multimammate rat Mastomys coucha, differing in their prepatent and patent periods. Both rodents were simultaneously experimentally inoculated with viable oocysts of C. muris (strain TS03). Animals were dissected and screened for the presence of the parasite using a combined morphological approach and nested PCR (SSU rRNA) at different times after inoculation. The occurrence of first developmental stages of C. muris in stomach was detected at 2.5 DPI. The presence of Type II merogony, appearing 36 hours later than Type I merogony, was confirmed in both rodents. Oocysts exhibiting different size and thickness of their wall were observed from 5 DPI onwards in stomach of both host models. The early phase of parasitisation in BALB/c mice progressed rapidly, with a prepatent period of 7.5–10 days; whereas in M. coucha, the developmental stages of C. (en)
Title
  • Life cycle of Cryptosporidium muris in two rodents with different responses to parasitisation
  • Life cycle of Cryptosporidium muris in two rodents with different responses to parasitisation (en)
skos:prefLabel
  • Life cycle of Cryptosporidium muris in two rodents with different responses to parasitisation
  • Life cycle of Cryptosporidium muris in two rodents with different responses to parasitisation (en)
skos:notation
  • RIV/00216224:14310/14:00073486!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GAP505/11/1163), P(GPP506/10/P372), S
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
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  • 26161
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/14:00073486
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cryptosporidia development gastric oocyst pathology Type II merogony (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [6B90E356CE72]
http://linked.open...i/riv/nazevZdroje
  • Parasitology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 141
http://linked.open...iv/tvurceVysledku
  • Kváč, Martin
  • Sak, Bohumil
  • Valigurová, Andrea
  • Ilgová, Jana
  • Koudela, Břetislav
  • Melicherová, Janka
http://linked.open...ain/vavai/riv/wos
  • 000331903700013
issn
  • 0031-1820
number of pages
http://bibframe.org/vocab/doi
  • 10.1017/S0031182013001637
http://localhost/t...ganizacniJednotka
  • 14310
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