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  • Entomopathogenic nematodes (EPN) Heterorhabditis bacteriophora are obligate and lethal insect parasites. These EPN are symbiotically associated with entomopathogenic bacteria Photorhabdus luminescens creating the highly pathogenic nematobacterial complex that is able to kill the host within 24 to 48 hours. H. bacteriophora with its bacterial symbionts are able to infect a broad spectrum of insect species. Symbiotic bacteria help to digest host tissues and provide nutrients for themselves and developing nematodes. Drosophila larvae are suitable insect hosts and part of the tripartite model system (Drosophila – EPN - bacteria). In this study we examined transcriptional changes in Drosophila upon nematode infection. We compare gene expression in non- infected and infected fly larvae. We focused on the early time point of nematode infection and therefore infected Drosophila larvae using H. bacteriophora harbouring GFP-labelled P. luminescens bacteria.
  • Entomopathogenic nematodes (EPN) Heterorhabditis bacteriophora are obligate and lethal insect parasites. These EPN are symbiotically associated with entomopathogenic bacteria Photorhabdus luminescens creating the highly pathogenic nematobacterial complex that is able to kill the host within 24 to 48 hours. H. bacteriophora with its bacterial symbionts are able to infect a broad spectrum of insect species. Symbiotic bacteria help to digest host tissues and provide nutrients for themselves and developing nematodes. Drosophila larvae are suitable insect hosts and part of the tripartite model system (Drosophila – EPN - bacteria). In this study we examined transcriptional changes in Drosophila upon nematode infection. We compare gene expression in non- infected and infected fly larvae. We focused on the early time point of nematode infection and therefore infected Drosophila larvae using H. bacteriophora harbouring GFP-labelled P. luminescens bacteria. (en)
Title
  • Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila
  • Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila (en)
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  • Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila
  • Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila (en)
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  • RIV/00216224:14310/13:00069822!RIV14-MSM-14310___
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  • RIV/00216224:14310/13:00069822
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  • Drosophila; entomopathogenic nematodes (en)
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  • [A0B3C027CF8D]
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  • Dobeš, Pavel
  • Hyršl, Pavel
  • Kučerová, Lucie
  • Strnad, Hynek
  • Theopold, Ulrich
  • Wang, Zhi
  • Žurovec, Michal
  • Markus, Robert
  • Arefin, Badrul
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  • 14310
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