About: DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin.     Goto   Sponge   NotDistinct   Permalink

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  • Haloalkane dehalogenases are known as bacterial enzymes cleaving a carbon-halogen bond in halogenated compounds. Here we report the first biochemically characterized non-microbial haloalkane dehalogenase DspA from Strongylocentrotus purpuratus. The enzyme shows a preference for terminally brominated hydrocarbons and enantioselectivity towards beta-brominated alkanes. Moreover, we identified other putative dehalogenases of eukaryotic origin, representing targets for future experiments to discover dehalogenases with novel catalytic properties.
  • Haloalkane dehalogenases are known as bacterial enzymes cleaving a carbon-halogen bond in halogenated compounds. Here we report the first biochemically characterized non-microbial haloalkane dehalogenase DspA from Strongylocentrotus purpuratus. The enzyme shows a preference for terminally brominated hydrocarbons and enantioselectivity towards beta-brominated alkanes. Moreover, we identified other putative dehalogenases of eukaryotic origin, representing targets for future experiments to discover dehalogenases with novel catalytic properties. (en)
Title
  • DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin.
  • DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin. (en)
skos:prefLabel
  • DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin.
  • DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin. (en)
skos:notation
  • RIV/00216224:14310/13:00065807!RIV14-MSM-14310___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ED0001/01/01), P(GAP207/12/0775), P(IAA401630901), S
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  • 11
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  • 70659
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/13:00065807
http://linked.open...riv/jazykVysledku
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  • Haloalkane Dehalogenase (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [301E924F641D]
http://linked.open...i/riv/nazevZdroje
  • Biochimie
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http://linked.open...v/svazekPeriodika
  • 95
http://linked.open...iv/tvurceVysledku
  • Chaloupková, Radka
  • Damborský, Jiří
  • Fořtová, Andrea
  • Koudeláková, Táňa
  • Štěpánková, Veronika
  • Pálková, Lenka
  • Šebestová, Eva
http://linked.open...ain/vavai/riv/wos
  • 000325831000015
issn
  • 0300-9084
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.biochi.2013.07.025
http://localhost/t...ganizacniJednotka
  • 14310
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