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Description
| - Antioxidant enzymes play a major role in the defense against pro-oxidative effects of xenobiotics and prooxidant plant allelochemicals in insects. We posed the hypothesis that eicosanoids also mediate antioxidant enzymatic defense reactions to pro-oxidant challenge. To test this idea, we reared first-instar larvae of Galleria mellonella (L.) with esculetin (0.001%), dexamethasone (0.001%) and phenidone (0.1%) to seventh-instars. Newly ecdysed seventh-instars were then fed on artificial diet containing 0.05% xanthotoxin (XA) for 2 days. High dietary XA concentrations (0.005 and 0.1%) were associated with increasing MDA and carbonyl content (by 3-fold) and antioxidant enzyme activities, superoxide dismutase (SOD) (by 3-fold) and catalase (CAT) (by 4-fold), and glutathione-dependent enzymes, glutathione S-transferase (GST) (by 15-fold) and glutathione peroxidase (GPx) (by 7-fold).
- Antioxidant enzymes play a major role in the defense against pro-oxidative effects of xenobiotics and prooxidant plant allelochemicals in insects. We posed the hypothesis that eicosanoids also mediate antioxidant enzymatic defense reactions to pro-oxidant challenge. To test this idea, we reared first-instar larvae of Galleria mellonella (L.) with esculetin (0.001%), dexamethasone (0.001%) and phenidone (0.1%) to seventh-instars. Newly ecdysed seventh-instars were then fed on artificial diet containing 0.05% xanthotoxin (XA) for 2 days. High dietary XA concentrations (0.005 and 0.1%) were associated with increasing MDA and carbonyl content (by 3-fold) and antioxidant enzyme activities, superoxide dismutase (SOD) (by 3-fold) and catalase (CAT) (by 4-fold), and glutathione-dependent enzymes, glutathione S-transferase (GST) (by 15-fold) and glutathione peroxidase (GPx) (by 7-fold). (en)
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Title
| - Eicosanoids mediate hemolymph oxidative and antioxidative response in larvae of Galleria mellonella
- Eicosanoids mediate hemolymph oxidative and antioxidative response in larvae of Galleria mellonella (en)
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skos:prefLabel
| - Eicosanoids mediate hemolymph oxidative and antioxidative response in larvae of Galleria mellonella
- Eicosanoids mediate hemolymph oxidative and antioxidative response in larvae of Galleria mellonella (en)
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skos:notation
| - RIV/00216224:14310/12:00060850!RIV13-MSM-14310___
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/12:00060850
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Eicosanoids; Galleria mellonella; Antioxidant enzymes; Oxidative stress (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Hyršl, Pavel
- Büyükgüzel, Ender
- Büyükgüzel, Kemal
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http://localhost/t...ganizacniJednotka
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