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  • Cryptosporidia (Apicomplexa) have been recently recognized as one of the most ubiquitous parasites infecting gastrointestinal and respiratory tract of vertebrates. Localization of cryptosporidian developmental stages in the host epithelium has been the subject of extensive speculation for many years. Our published data support the term epicellular to reflect the cryptosporidian localization, rather than the term intracellular extracytoplasmic, used throughout the literature. Due to its peculiar localization, Cryptosporidium can derive nutrition while minimizing immunologic recognition and there is currently no effective treatment for cryptosporidiosis. In presented study, the life cycle of Cryptosporidium muris parasitizing gastric glands of experimentally infected laboratory rodents, Mastomys natalensis and BALB/c mice, has been analysed in detail. The main aim was to map the development of C. muris in hosts exhibiting different response to the parasitization.
  • Cryptosporidia (Apicomplexa) have been recently recognized as one of the most ubiquitous parasites infecting gastrointestinal and respiratory tract of vertebrates. Localization of cryptosporidian developmental stages in the host epithelium has been the subject of extensive speculation for many years. Our published data support the term epicellular to reflect the cryptosporidian localization, rather than the term intracellular extracytoplasmic, used throughout the literature. Due to its peculiar localization, Cryptosporidium can derive nutrition while minimizing immunologic recognition and there is currently no effective treatment for cryptosporidiosis. In presented study, the life cycle of Cryptosporidium muris parasitizing gastric glands of experimentally infected laboratory rodents, Mastomys natalensis and BALB/c mice, has been analysed in detail. The main aim was to map the development of C. muris in hosts exhibiting different response to the parasitization. (en)
Title
  • Life cycle of Cryptosporidium muris in experimental conditions
  • Life cycle of Cryptosporidium muris in experimental conditions (en)
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  • Life cycle of Cryptosporidium muris in experimental conditions
  • Life cycle of Cryptosporidium muris in experimental conditions (en)
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  • RIV/00216224:14310/12:00058216!RIV13-GA0-14310___
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  • RIV/00216224:14310/12:00058216
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  • cryptosporidia; development; life cycle; rodent; cell lines (en)
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  • [F71304FD5125]
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  • Kváč, Martin
  • Valigurová, Andrea
  • Ilgová, Jana
  • Koudela, Břetislav
  • Melicherová, Janka
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  • 14310
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