About: Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Intracellular ROS production significantly regulates the fate of various cell types through redox interaction with signal transduction pathways (reviewed in Hensley et al. 2000). Thus, the determination of the actual intracellular ROS level in cells is crucial for understanding the ROS role in the key processes governing differentiation, cellular death and carcinogenesis. Intracellular ROS are usually produced by non-phagocytic NADPH oxidases and mitochondria (Kowaltowski et al. 2009). Thus, mitochondria mass and membrane potential are often determined together with intracellular ROS production. A wide spectrum of fluorescent redox-sensitive probes for the determination of intracellular ROS production have been developed and employed in numerous studies (Soh 2006, Dickinson et al. 2009). Both the high sensitivity and the reproducibility of results of are directly connected with the preservation of the oxidized/reduced fluorescent probe inside the cell. Intracellular ROS production significantly regulates the fate of various cell types through redox interaction with signal transduction pathways (reviewed in Hensley et al. 2000). Thus, the determination of the actual intracellular ROS level in cells is crucial for understanding the ROS role in the key processes governing differentiation, cellular death and carcinogenesis. Intracellular ROS are usually produced by non-phagocytic NADPH oxidases and mitochondria (Kowaltowski et al. 2009). Thus, mitochondria mass and membrane potential are often determined together with intracellular ROS production. A wide spectrum of fluorescent redox-sensitive probes for the determination of intracellular ROS production have been developed and employed in numerous studies (Soh 2006, Dickinson et al. 2009). Both the high sensitivity and the reproducibility of results of are directly connected with the preservation of the oxidized/reduced fluorescent probe inside the cell. (en)
Title	Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters (en)
skos:prefLabel	Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters Commonly used ROS-sensitive fluorescent probes are substrates of ABC transporters (en)
skos:notation	RIV/00216224:14310/11:00050554!RIV12-GA0-14310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GA301/08/0717), S
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Pekarová, Michaela Kotasová, Hana Gudernová, Iva Pacherník, Jiří Kubala, Lukáš Šrámková, Zuzana
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	190949
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/11:00050554
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ABC transporters; mitochondria; fluorescent probe (en)
http://linked.open.../riv/klicoveSlovo	ABC transporters fluorescent probe mitochondria
http://linked.open...ontrolniKodProRIV	[D15213220080]
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Gp130 receptor-mediated differentiation of ES cells
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Gudernová, Iva Kotasová, Hana Kubala, Lukáš Pacherník, Jiří Pekarová, Michaela Procházková, Jiřina Sarkadi, Balazs Šrámková, Zuzana
http://localhost/t...ganizacniJednotka	14310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software