About: Spectroscopic study of protonation of cytosine-containing oligonucleotides

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cytosine is an important building block of nucleic acids taking part in the process of genetic information transfer and transfer of energy of biologically important compounds by means of coenzymes. Due to acidobasic properties of bioligands, the presence of protonated species is dependent on the protonation constants. It was also shown that oligonucleotides (ODNs) concerning cytosine can form the so called structural i motif as a consequence of probable stabilization of the secondary structure of biomacromolecules. The aim of this work was to determine the protonation constants of ODNs varying the number of bases in order to see their influence on thermodynamic stability of studied ligands. Cytosine is an important building block of nucleic acids taking part in the process of genetic information transfer and transfer of energy of biologically important compounds by means of coenzymes. Due to acidobasic properties of bioligands, the presence of protonated species is dependent on the protonation constants. It was also shown that oligonucleotides (ODNs) concerning cytosine can form the so called structural i motif as a consequence of probable stabilization of the secondary structure of biomacromolecules. The aim of this work was to determine the protonation constants of ODNs varying the number of bases in order to see their influence on thermodynamic stability of studied ligands. (en)
Title	Spectroscopic study of protonation of cytosine-containing oligonucleotides Spectroscopic study of protonation of cytosine-containing oligonucleotides (en)
skos:prefLabel	Spectroscopic study of protonation of cytosine-containing oligonucleotides Spectroscopic study of protonation of cytosine-containing oligonucleotides (en)
skos:notation	RIV/00216224:14310/10:00044422!RIV11-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC06035), Z(MSM0021622412)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Kristová, Petra Holubová, Sylvie Trnková, Libuše Lubal, Přemysl Farková, Marta Vrbková, Blanka
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	289162
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/10:00044422
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	spectroscopy; cytosine; protonation constant (en)
http://linked.open.../riv/klicoveSlovo	spectroscopy cytosine protonation constant
http://linked.open...ontrolniKodProRIV	[118393F114C1]
http://linked.open...v/mistoKonaniAkce	Litomyšl
http://linked.open...i/riv/mistoVydani	Pardubice
http://linked.open...i/riv/nazevZdroje	Sborníi 14. česko - slovenské spektroskopické konference
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine.
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Holubová, Sylvie Lubal, Přemysl Trnková, Libuše Farková, Marta Vrbková, Blanka Kristová, Petra
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2010-05-31 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
number of pages	100 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Spektroskopická společnost Jana Marka Marci
https://schema.org/isbn	978-80-7395-282-2
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Spectroscopic study of protonation of cytosine-containing oligonucleotides Spectroscopic study of protonation of cytosine-containing oligonucleotides Spectroscopic study of protonation of cytosine-containing oligonucleotides

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