About: Diversity of prophages in dominant Staphylococcus aureus> clonal lineages

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Temperate bacteriophages play an important role in the pathogenicity of Staphylococcus aureus, for instance, by mediating the horizontal gene transfer of virulence factors. Here we established a classification scheme for staphylococcal prophages of the major Siphoviridae family based on integrase gene polymorphism. Seventy-one published genome sequences of staphylococcal phages were clustered into distinct integrase groups which were related to the chromosomal integration site and to the encoded virulence gene content. Analysis of three marker modules (lysogeny, tail, and lysis) for phage functional units revealed that these phages exhibit different degrees of genome mosaicism. The prevalence of prophages in a representative S. aureus strain collection consisting of 386 isolates of diverse origin was determined. By linking the phage content to dominant S. Temperate bacteriophages play an important role in the pathogenicity of Staphylococcus aureus, for instance, by mediating the horizontal gene transfer of virulence factors. Here we established a classification scheme for staphylococcal prophages of the major Siphoviridae family based on integrase gene polymorphism. Seventy-one published genome sequences of staphylococcal phages were clustered into distinct integrase groups which were related to the chromosomal integration site and to the encoded virulence gene content. Analysis of three marker modules (lysogeny, tail, and lysis) for phage functional units revealed that these phages exhibit different degrees of genome mosaicism. The prevalence of prophages in a representative S. aureus strain collection consisting of 386 isolates of diverse origin was determined. By linking the phage content to dominant S. (en)
Title	Diversity of prophages in dominant Staphylococcus aureus> clonal lineages Diversity of prophages in dominant Staphylococcus aureus> clonal lineages (en)
skos:prefLabel	Diversity of prophages in dominant Staphylococcus aureus> clonal lineages Diversity of prophages in dominant Staphylococcus aureus> clonal lineages (en)
skos:notation	RIV/00216224:14310/09:00035545!RIV11-MSM-14310___
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Doškař, Jiří Pantůček, Roman
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	310932
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/09:00035545
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Staphylococcus aureus; bacteriophages; accessory genome; clonal lineages; lysogeny (en)
http://linked.open.../riv/klicoveSlovo	Staphylococcus aureus bacteriophages lysogeny accessory genome clonal lineages
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F420A895B92C]
http://linked.open...i/riv/nazevZdroje	Journal of Bacteriology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	191
http://linked.open...iv/tvurceVysledku	Doškař, Jiří Pantůček, Roman Goerke, Christiane Bröker, Barbara M. Grumann, Dorothee Holtfreter, Silvia Schulte, Berit Wolz, Christiane Zink, Manuel
http://linked.open...ain/vavai/riv/wos	000266041300005
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	0021-9193
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Diversity of prophages in dominant Staphylococcus aureus> clonal lineages Diversity of prophages in dominant Staphylococcus aureus> clonal lineages Diversity of prophages in dominant Staphylococcus aureus> clonal lineages

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