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rdf:type
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Description
| - A series of four bicyclic cores were prepared and evaluated and cyclin-dependent kinase-2 (CDK2) inhibitors. From the in vitro and cell-based analysis, the pyrazolo[1,5-a]pyrimidine core (represented by 9) emerged as the superior for further elaboration in the identification of novel CDK2 inhibitors.
- A series of four bicyclic cores were prepared and evaluated and cyclin-dependent kinase-2 (CDK2) inhibitors. From the in vitro and cell-based analysis, the pyrazolo[1,5-a]pyrimidine core (represented by 9) emerged as the superior for further elaboration in the identification of novel CDK2 inhibitors. (en)
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Title
| - Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors
- Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors (en)
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skos:prefLabel
| - Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors
- Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors (en)
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skos:notation
| - RIV/00216224:14310/07:00035882!RIV10-MSM-14310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/07:00035882
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - kinases; template; CDK2 (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Bioorganic & Medicinal Chemistry Letters
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Alvarez, Carmen
- Duca, Jose
- Dwyer, Michael
- Fischmann, Thierry
- Guzi, Timothy
- Keertikar, Kerry
- Madison, Vincent
- Parry, David
- Paruch, Kamil
- Seghezzi, Wolfgang
- Wiswell, Derek
- Shanahan, Frances
- Doll, Ronald
- Hruza, Alan
- Lees, Emma
- Sgambellone, Nicole
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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