About: Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) Thiosemicarbazide     Goto   Sponge   NotDistinct   Permalink

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  • Two new 1-substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) thiosemicarbazides 3 and 5 were formed by multistep domino reaction of imidoyl isothiocyanate derivative 1 with 1,1-di-R hydrazine in acetone solution. Applied hydrazine hydrate under the same reaction condition afforded 4-(2-phenylquinazolin-4(3H)-ylidene)-2-(prop-1-en-2-yl)-1- (propan-2-lidene) thiosemicarbazide (7) via six step three component domino reaction. Compounds 3, 5 and 7 were identified by CHNS elemental analysis, 1H-NMR, 13C-NMR spectral data and their correlation with ones from known structural motives.
  • Two new 1-substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) thiosemicarbazides 3 and 5 were formed by multistep domino reaction of imidoyl isothiocyanate derivative 1 with 1,1-di-R hydrazine in acetone solution. Applied hydrazine hydrate under the same reaction condition afforded 4-(2-phenylquinazolin-4(3H)-ylidene)-2-(prop-1-en-2-yl)-1- (propan-2-lidene) thiosemicarbazide (7) via six step three component domino reaction. Compounds 3, 5 and 7 were identified by CHNS elemental analysis, 1H-NMR, 13C-NMR spectral data and their correlation with ones from known structural motives. (en)
Title
  • Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) Thiosemicarbazide
  • Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) Thiosemicarbazide (en)
skos:prefLabel
  • Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) Thiosemicarbazide
  • Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene) Thiosemicarbazide (en)
skos:notation
  • RIV/00216224:14310/07:00020614!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(2A-1TP1/090), P(GA203/01/1333), Z(MSM 143100011)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 453937
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  • RIV/00216224:14310/07:00020614
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http://linked.open.../riv/klicovaSlova
  • quinazoline; thiosemicarbazide; domino reaction; hydrogen bond interaction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [602E4B0788CF]
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  • Basel, Switzerland
http://linked.open...i/riv/mistoVydani
  • Basel, Switzerland
http://linked.open...i/riv/nazevZdroje
  • 11th INTERNATIONAL ELECTRONIC CONFERENCE ON SYNTHETIC ORGANIC CHEMISTRY
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http://linked.open...UplatneniVysledku
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  • Pazdera, Pavel
  • Fathala, Mohamed Walid
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http://linked.open...n/vavai/riv/zamer
number of pages
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  • MDPI, Matthaeusstrasse 11, CH-4057 Basel, Switzerland
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  • 3-906980-19-7
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  • 14310
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