About: Structural protein analysis of the polyvalent staphylococcal bacteriophage 812

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Phage 812 is a polyvalent phage with a very broad host range in the genus Staphylococcus, which makes it a suitable candidate for phage therapy of staphylococcal infections. This proteomic study, combining the results of both 1-DE and 2-DE followed by PMF, led to the identification of 24 virion proteins. Twenty new proteins, not yet identified by proteome analysis of closely related staphylococcal phages K and G1 were identified using this approach. Fifteen proteins were assigned unambiguously to the head-tail genome module; the remaining nine proteins are encoded by genes of the left or right arms of the phage genome. As expected, the most abundant proteins in the electrophoretic patterns are the major capsid protein, the major tail sheath protein and proteins identical to ORF 50 and ORF 95 of phage K, although their function is only putative. Phage 812 is a polyvalent phage with a very broad host range in the genus Staphylococcus, which makes it a suitable candidate for phage therapy of staphylococcal infections. This proteomic study, combining the results of both 1-DE and 2-DE followed by PMF, led to the identification of 24 virion proteins. Twenty new proteins, not yet identified by proteome analysis of closely related staphylococcal phages K and G1 were identified using this approach. Fifteen proteins were assigned unambiguously to the head-tail genome module; the remaining nine proteins are encoded by genes of the left or right arms of the phage genome. As expected, the most abundant proteins in the electrophoretic patterns are the major capsid protein, the major tail sheath protein and proteins identical to ORF 50 and ORF 95 of phage K, although their function is only putative. (en)
Title	Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 (en)
skos:prefLabel	Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 (en)
skos:notation	RIV/00216224:14310/07:00020066!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/03/0515), P(OBVLAJEP20031), Z(MO0FVZ0000604), Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Preisler, Jan Kašpárek, Petr Hernychová, Lenka Doškař, Jiří Růžičková, Vladislava Zdráhal, Zbyněk Pantůček, Roman Konečná, Hana Eyer, Luděk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	452876
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00020066
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	staphylococcus bacteriophage; proteome; Myoviridae; Staphylococcus aureus; phage therapy (en)
http://linked.open.../riv/klicoveSlovo	staphylococcus bacteriophage Staphylococcus aureus Myoviridae proteome phage therapy
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[821346AB3A1B]
http://linked.open...i/riv/nazevZdroje	Proteomics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Integrated genome and proteome analysis of therapeutically important bacteriophages by combination of electrophoresis and mass spectrometry INFECTION 2 - The use of proteome analysis in microbiological diagnostics of infections whose aetiological agentsare on the listof BW-agents
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Doškař, Jiří Hernychová, Lenka Konečná, Hana Pantůček, Roman Preisler, Jan Růžičková, Vladislava Zdráhal, Zbyněk Eyer, Luděk Kašpárek, Petr
http://linked.open...ain/vavai/riv/wos	000243762900007
http://linked.open...n/vavai/riv/zamer	Informační zabezpečení krizového managementu pro oblast zdravotnictví Molecular basis of cell and tissue regulations
issn	1615-9853
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 Structural protein analysis of the polyvalent staphylococcal bacteriophage 812 Structural protein analysis of the polyvalent staphylococcal bacteriophage 812

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