About: GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes.

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About: GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Azaarenes are nitrogen-containing polyaromatic heterocyclic compounds (NPAHs). The majority of the azaarenes found in the environment originate from anthropogenic sources. Concentrations of NPAHs found in the environment are reported to be one to two orders of magnitude lower than polycyclic aromatic hydrocarbons (PAHs) concentrations, yet their biological effects can be of similar magnitude.Azaarenes are nitrogen-containing polyaromatic heterocyclic compounds (NPAHs). The majority of the azaarenes found in the environment originate from anthropogenic sources. Concentrations of NPAHs found in the environment are reported to be one to two orders of magnitude lower than polycyclic aromatic hydrocarbons (PAHs) concentrations, yet their biological effects can be of similar magnitude. To assess the toxic and genotoxic activity, a green fluorescent protein (GFP) assay based on the yeast Saccharomyces cerevisiae was selected. Azaarenes are nitrogen-containing polyaromatic heterocyclic compounds (NPAHs). The majority of the azaarenes found in the environment originate from anthropogenic sources. Concentrations of NPAHs found in the environment are reported to be one to two orders of magnitude lower than polycyclic aromatic hydrocarbons (PAHs) concentrations, yet their biological effects can be of similar magnitude.Azaarenes are nitrogen-containing polyaromatic heterocyclic compounds (NPAHs). The majority of the azaarenes found in the environment originate from anthropogenic sources. Concentrations of NPAHs found in the environment are reported to be one to two orders of magnitude lower than polycyclic aromatic hydrocarbons (PAHs) concentrations, yet their biological effects can be of similar magnitude. To assess the toxic and genotoxic activity, a green fluorescent protein (GFP) assay based on the yeast Saccharomyces cerevisiae was selected. (en)
Title	GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. (en)
skos:prefLabel	GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. (en)
skos:notation	RIV/00216224:14310/06:00018644!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622412)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Flegrová, Zuzana Holoubek, Ivan Čupr, Pavel Bartoš, Tomáš Škarek, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	477078
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/06:00018644
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	azaarenes; GFP yeast bioassay; genotoxicity; toxicity (en)
http://linked.open.../riv/klicoveSlovo	genotoxicity toxicity GFP yeast bioassay azaarenes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[0B8DC01643AC]
http://linked.open...i/riv/nazevZdroje	Environmental Toxicology
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Holoubek, Ivan Čupr, Pavel Bartoš, Tomáš Flegrová, Zuzana Škarek, Michal Letzsch, Štefan
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
issn	1520-4081
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes. GFP assay as a sensitive eukaryotic screening model to detect toxic and genotoxic activity of azaarenes.

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