About: High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma

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About: High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Neuroblastoma (NB) is a genetically very heterogeneous pediatric malignant tumor. The clinical course of NB vary markedly. Therefore molecular and cytogenetic markers are studied as strong predictors of clinical outcome, to amnedclinical staging and aid in treatment planning. This malignancy is characterized by a broad spectrum of clinical behavior. Low-, intermediate, and high-risk groups have been defined based upon expected outcome following conventional therapy using both clinical and biological criteria. The criteria currently used to assign risk-group are as follows: Clinical stage, MYCN status, Shimada histology and DNA ploidy. Recently, other cytogenetic changes as 1p, 3p, 11q deletions and 17q rearrangements may also have prognostic value. Neuroblastoma (NB) is a genetically very heterogeneous pediatric malignant tumor. The clinical course of NB vary markedly. Therefore molecular and cytogenetic markers are studied as strong predictors of clinical outcome, to amnedclinical staging and aid in treatment planning. This malignancy is characterized by a broad spectrum of clinical behavior. Low-, intermediate, and high-risk groups have been defined based upon expected outcome following conventional therapy using both clinical and biological criteria. The criteria currently used to assign risk-group are as follows: Clinical stage, MYCN status, Shimada histology and DNA ploidy. Recently, other cytogenetic changes as 1p, 3p, 11q deletions and 17q rearrangements may also have prognostic value. (en)
Title	High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma (en)
skos:prefLabel	High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma (en)
skos:notation	RIV/00216224:14310/06:00017834!RIV10-MZ0-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9125), Z(MSM0021622415)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Štěrba, Jaroslav Vranová, Vladimíra Kuglík, Petr Žežulková, Dita Filková, Hana Oltová, Alexandra Štefančíková, Lenka Nečesalová, Eva
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	477719
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/06:00017834
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	neuroblastoma; high resolution comparative genomic hybridization; chromosomal aberration; prognostic factors (en)
http://linked.open.../riv/klicoveSlovo	chromosomal aberration prognostic factors neuroblastoma high resolution comparative genomic hybridization
http://linked.open...ontrolniKodProRIV	[23AD839961DA]
http://linked.open...v/mistoKonaniAkce	Amsterdam
http://linked.open...i/riv/mistoVydani	Amsterdam
http://linked.open...i/riv/nazevZdroje	Europen Journal of Human Genetics
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Importance of molecular cytogenetic markers for diagnosis and prediction of embryonal childhood tumors.
http://linked.open...UplatneniVysledku	2006
http://linked.open...iv/tvurceVysledku	Kuglík, Petr Vranová, Vladimíra Štěrba, Jaroslav Filková, Hana Oltová, Alexandra Štefančíková, Lenka Mazánek, Pavel Nečesalová, Eva Žežulková, Dita
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2006-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1018-4813
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	ESHG
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma High-resolution of comparative genomic hybridization improves detection of chromosomal aberrations with prognostic significance in neuroblastoma

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