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Description
  • The retinoic signaling pathway could be one of the important targets for endocrine disruptors because of the fact that retinoids control large number of vital processes in the organism and that their signaling is very complexly regulated. We developed an in vitro model for evaluation of anti/retinoic action of xenobiotics. The model is based on murine embryonic carcinoma cell line P19, which retains its pluripotent character so that it is able to differentiate into cells of the all three germ layers.
  • The retinoic signaling pathway could be one of the important targets for endocrine disruptors because of the fact that retinoids control large number of vital processes in the organism and that their signaling is very complexly regulated. We developed an in vitro model for evaluation of anti/retinoic action of xenobiotics. The model is based on murine embryonic carcinoma cell line P19, which retains its pluripotent character so that it is able to differentiate into cells of the all three germ layers. (en)
Title
  • Assessment of retinoic toxicity in several types of complex environmental samples using P19/A15 cell line
  • Assessment of retinoic toxicity in several types of complex environmental samples using P19/A15 cell line (en)
skos:prefLabel
  • Assessment of retinoic toxicity in several types of complex environmental samples using P19/A15 cell line
  • Assessment of retinoic toxicity in several types of complex environmental samples using P19/A15 cell line (en)
skos:notation
  • RIV/00216224:14310/06:00016461!RIV11-GA0-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GP525/05/P160), Z(MSM0021622412)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 466157
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/06:00016461
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • endocrine disruption; retinoid; complex samples (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [335808F0F4C6]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Bláha, Luděk
  • Giesy, John Paul
  • Hilscherová, Klára
  • Novák, Jiří
  • Beníšek, Martin
  • Štěpánková, Tereza
http://linked.open...n/vavai/riv/zamer
http://localhost/t...ganizacniJednotka
  • 14310
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