About: Electrochemical sensors for detection of acetylsalicylic acid

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Acetylsalicylic acid (AcSA), or aspirin, was introduced in the late 1890s and has been used to treat a variety of inflammatory conditions. The aim of this work was to suggest electrochemical sensor for acetylsalicylic detection. Primarily, we utilized square wave voltammetry (SWV) using both carbon paste electrode (CPE) and of graphite pencil electrode (GPE) as working ones to indirect determination of AcSA. The principle of indirect determination of AcSA bases in its hydrolysis on salicylic acid (SA), which is consequently detected. Thus, we optimized both determination of SA and conditions for AcSA hydrolysis and found out that the most suitable frequency, amplitude, step potential and the composition and pH of the supporting electrolyte for the determination of SA was 260 Hz, 50 mV, 10 mV and Britton-Robinson buffer (pH 1.81), respectively. The detection limit (S/N = 3) of the SA was 1.3 ng/ml. After that, we aimed on indirect determination of AcSA by SWV CPE. Acetylsalicylic acid (AcSA), or aspirin, was introduced in the late 1890s and has been used to treat a variety of inflammatory conditions. The aim of this work was to suggest electrochemical sensor for acetylsalicylic detection. Primarily, we utilized square wave voltammetry (SWV) using both carbon paste electrode (CPE) and of graphite pencil electrode (GPE) as working ones to indirect determination of AcSA. The principle of indirect determination of AcSA bases in its hydrolysis on salicylic acid (SA), which is consequently detected. Thus, we optimized both determination of SA and conditions for AcSA hydrolysis and found out that the most suitable frequency, amplitude, step potential and the composition and pH of the supporting electrolyte for the determination of SA was 260 Hz, 50 mV, 10 mV and Britton-Robinson buffer (pH 1.81), respectively. The detection limit (S/N = 3) of the SA was 1.3 ng/ml. After that, we aimed on indirect determination of AcSA by SWV CPE. (en)
Title	Electrochemical sensors for detection of acetylsalicylic acid Electrochemical sensors for detection of acetylsalicylic acid (en)
skos:prefLabel	Electrochemical sensors for detection of acetylsalicylic acid Electrochemical sensors for detection of acetylsalicylic acid (en)
skos:notation	RIV/00216224:14310/06:00016396!RIV10-GA0-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1A8666), P(1M06030), P(GP525/04/P132), Z(MSM6215712402)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Křížková, Soňa Adam, Vojtěch Kizek, René Potěšil, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	473767
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/06:00016396
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Electrochemistry; sensors; acetylsalicylic acid (en)
http://linked.open.../riv/klicoveSlovo	Electrochemistry sensors acetylsalicylic acid
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[E5A68B1380ED]
http://linked.open...i/riv/nazevZdroje	SENSORS
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Verification of antidiabetic effect of ethnobotanicaly important herbal medicines Functional genomics and proteomics for crop improvement Study of protection mechanisms for stress-induced by heavy metals
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Beklová, Miroslava Babula, P. Horna, Aleš Kizek, René Křížková, Soňa Havel, L. Potěšil, David Petřek, J. Petrolvá, J. Šupalková, V.
http://linked.open...n/vavai/riv/zamer	Veterinary aspects of food safety and quality
issn	1424-8220
number of pages	15 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Electrochemical sensors for detection of acetylsalicylic acid Electrochemical sensors for detection of acetylsalicylic acid

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