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  • Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental polygenetic heritable disorder that includes inattention, excessive motor activity, impulsivity and distractibility. In the past few years, interest in the molecular genetics of ADHD has grown enormously, with many groups searching for susceptibility genes. Dopaminergic genes have been prime candidates in the search for the genetic factors underlying novelty seeking because of the central role that dopamine plays in the brain's reward system. However, the findings are not conclusive and other new polymorphisms in different gene backgrounds are investigated. We have investigated whether there is an association between genes involving nervous system - cytokines, including IL-2, IL-6, and tumor necrosis factor-alpha (TNF-alpha).
  • Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental polygenetic heritable disorder that includes inattention, excessive motor activity, impulsivity and distractibility. In the past few years, interest in the molecular genetics of ADHD has grown enormously, with many groups searching for susceptibility genes. Dopaminergic genes have been prime candidates in the search for the genetic factors underlying novelty seeking because of the central role that dopamine plays in the brain's reward system. However, the findings are not conclusive and other new polymorphisms in different gene backgrounds are investigated. We have investigated whether there is an association between genes involving nervous system - cytokines, including IL-2, IL-6, and tumor necrosis factor-alpha (TNF-alpha). (en)
Title
  • THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN
  • THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN (en)
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  • THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN
  • THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN (en)
skos:notation
  • RIV/00216224:14310/05:00015217!RIV10-MZ0-14310___
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  • P(NF6520)
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  • 513202
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  • RIV/00216224:14310/05:00015217
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  • ADHD association IL-6 gene polymorphism (en)
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  • [CE62D4D2EEE7]
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  • IX. Pracovní setkání biochemiků a molekulárních biologů
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  • Drtílková, Ivana
  • Šerý, Omar
  • Theiner, Pavel
  • Štaif, Radim
  • Pitelová, Renáta
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  • Masarykova univerzita v Brně
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  • 80-210-3635-4
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  • 14310
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