About: In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Sepsis is a greatly feared complication of total joint arthroplasty. One key question is how to prevent periopera-tive bacterial adherence, and therefore the potential for infectious complications. The objective of our study was to appraise the emerging capacity of staphylococcal survival on prosthetic materials and to analyze the in vitro eects of gentamicin and vancomycin loaded polymethylmethacrylate (PMMA) cement on bacterial adherence and growth. Hospital acquired staphylococcal strains were systematically inoculated on four orthopedic materials (ultrahigh mo-lecular weight polyethylene, PMMA without antibiotic, commercially produced PMMA loaded with gentamicin, and manually mixed PMMA loaded with gentamicin and vancomycin). Staphylococci were identied using culture and biochemical tests. The inoculated material was allowed to incubate in a liquid broth growth media and subsequently prepared for scanning electron microscopy and bacterial growth quantication. Sepsis is a greatly feared complication of total joint arthroplasty. One key question is how to prevent periopera-tive bacterial adherence, and therefore the potential for infectious complications. The objective of our study was to appraise the emerging capacity of staphylococcal survival on prosthetic materials and to analyze the in vitro eects of gentamicin and vancomycin loaded polymethylmethacrylate (PMMA) cement on bacterial adherence and growth. Hospital acquired staphylococcal strains were systematically inoculated on four orthopedic materials (ultrahigh mo-lecular weight polyethylene, PMMA without antibiotic, commercially produced PMMA loaded with gentamicin, and manually mixed PMMA loaded with gentamicin and vancomycin). Staphylococci were identied using culture and biochemical tests. The inoculated material was allowed to incubate in a liquid broth growth media and subsequently prepared for scanning electron microscopy and bacterial growth quantication. (en)
Title	In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection (en)
skos:prefLabel	In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection (en)
skos:notation	RIV/00216224:14310/05:00013848!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	KOLÁŘ, Milan Pantůček, Roman
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	524487
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/05:00013848
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Prosthetic joint infection; Polymethylmethacrylate; Antibiotic loaded cement; Vancomycin; Gentamicin; Staphylococcus aureus; Staphylococcus epidermidis (en)
http://linked.open.../riv/klicoveSlovo	Gentamicin Staphylococcus aureus Staphylococcus epidermidis Prosthetic joint infection Vancomycin Antibiotic loaded cement Polymethylmethacrylate
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[CCF7577A5A50]
http://linked.open...i/riv/nazevZdroje	Biomedical Papers
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	149
http://linked.open...iv/tvurceVysledku	Gallo, Jiří Kolář, Milan Pantůček, Roman Novotný, Radek Kesselová, Michaela Florschütz, Anthony V.
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1213-8118
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	In vitro testing of vancomycin - gentamicin loaded bone cement to prevent prosthetic joint infection

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