About: Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains

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About: Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Despite the medical importance of trichomoniasis, little is known about the genetic relatedness of Trichomonas vaginalis strains with similar biological characteristics. Furthermore, the distribution of endobionts such as mycoplasmas or Trichomonas vaginalis virus (TVV) in the T. vaginalis metapopulation is poorly characterised. RESULTS: We assayed the relationship between 20 strains of T. vaginalis from 8 countries using the Random Amplified Polymorphic DNA (RAPD) analysis with 27 random primers. The genealogical tree was constructed and its bootstrap values were computed using the program FreeTree. Using the permutation tail probability tests we found that the topology of the tree reflected both the pattern of resistance to metronidazole (the major anti-trichomonal drug) (p < 0.01) and the pattern of infection of strains by mycoplasmas (p < 0.05). However, the tree did not reflect pattern of virulence, geographic origin or infection by TVV. Despite the medical importance of trichomoniasis, little is known about the genetic relatedness of Trichomonas vaginalis strains with similar biological characteristics. Furthermore, the distribution of endobionts such as mycoplasmas or Trichomonas vaginalis virus (TVV) in the T. vaginalis metapopulation is poorly characterised. RESULTS: We assayed the relationship between 20 strains of T. vaginalis from 8 countries using the Random Amplified Polymorphic DNA (RAPD) analysis with 27 random primers. The genealogical tree was constructed and its bootstrap values were computed using the program FreeTree. Using the permutation tail probability tests we found that the topology of the tree reflected both the pattern of resistance to metronidazole (the major anti-trichomonal drug) (p < 0.01) and the pattern of infection of strains by mycoplasmas (p < 0.05). However, the tree did not reflect pattern of virulence, geographic origin or infection by TVV. (en)
Title	Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains (en)
skos:prefLabel	Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains Concordance between genetic relatedness and phenotypic similarities of Trichomonas vaginalis strains (en)
skos:notation	RIV/00216224:14310/01:00036250!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(MSM 113100004)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Vaňáčová, Štěpánka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	676223
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/01:00036250
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Trichomonads; phylogeny; RAPD; PCR; virulence; metronidazole resistence; dsRNA virus (en)
http://linked.open.../riv/klicoveSlovo	PCR phylogeny virulence RAPD metronidazole resistence Trichomonads dsRNA virus
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[1673B050C26D]
http://linked.open...i/riv/nazevZdroje	BMC Evolutionary Biology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	1
http://linked.open...iv/tvurceVysledku	Flegr, Jaroslav Kulda, Jaroslav Vaňáčová, Štěpánka Hampl, Vladimir
http://linked.open...ain/vavai/riv/wos	000170275500017
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100004
issn	1471-2148
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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