About: Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells

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About: Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To monitor apoptotic changes, we followed several parameters including cell viability, DNA integrity and telomerase activity.Preapoptotic phase has been achieved by exposure of cells to 50mM cadmium for 3 days.At that time the cell culture retains more than 95% viability although the majority of DNA is fragmented into 50-200 kb.Integrity of DNA is reestablished within two days after cadmium removal suggesting that an efficient DNA repair process has occurred.In parallel, a significant increase of telomerase activity in cell extracts is observed.The data suggest an involvement of telomerase in plant chromosome healing in response to damage caused by genotoxic agents. To monitor apoptotic changes, we followed several parameters including cell viability, DNA integrity and telomerase activity.Preapoptotic phase has been achieved by exposure of cells to 50mM cadmium for 3 days.At that time the cell culture retains more than 95% viability although the majority of DNA is fragmented into 50-200 kb.Integrity of DNA is reestablished within two days after cadmium removal suggesting that an efficient DNA repair process has occurred.In parallel, a significant increase of telomerase activity in cell extracts is observed.The data suggest an involvement of telomerase in plant chromosome healing in response to damage caused by genotoxic agents. (en)
Title	Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells (en)
skos:prefLabel	Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells Reversibility of cadmium-induced apoptosis is associated with increased level of telomerase activity in tobacco TBY-2 cells (en)
skos:notation	RIV/00216224:14310/01:00005257!RIV/2002/MSM/143102/N
http://linked.open.../vavai/riv/strany	963
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM 143100008)
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Kovařík, Aleš Fulnečková, Jana Fojtová, Miloslava Fajkus, Jiří
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	694697
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/01:00005257
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cadmium-induced apoptosis; tobacco (en)
http://linked.open.../riv/klicoveSlovo	cadmium-induced apoptosis tobacco
http://linked.open...ontrolniKodProRIV	[713F0BE32E51]
http://linked.open...v/mistoKonaniAkce	New York
http://linked.open...i/riv/mistoVydani	New York
http://linked.open...i/riv/nazevZdroje	Journal of Biomolecular Structure and Dynamics
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...UplatneniVysledku	2001
http://linked.open...iv/tvurceVysledku	Kovařík, Aleš Fajkus, Jiří Fojtová, Miloslava Fulnečková, Jana
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2001-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20143100008
issn	0739-1102
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Adenine Press
http://localhost/t...ganizacniJednotka	14310

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