About: Escherichia coli strains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia     Goto   Sponge   NotDistinct   Permalink

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  • Background: Colorectal cancer (CRC) is the 3rd most common cancer worldwide and the Czech Republic has the 6th highest incidence of CRC worldwide. Large intestinal microbiota play in its etiopathogenesis important role. Bacteriocins are proteins, produced by bacteria from the Enterobacteriaceae family. The aim of our prospective study was to assess the colonization of large intestinal mucosa by Escherichia coli strains and to investigate their bacteriocin production. Methods: A total of 30 consecutive patients with colorectal adenoma, CRA (17 men, 13 women, aged 39–79, mean age 63 +/- 9), 30 patients with CRC (23 men, 7 women, aged 38–86, mean age 67 +/- 11) and 20 healthy controls (9 men, 11 women, age 23–84, mean age 55 +/- 15) were enrolled into prospective study. Mucosal biopsies were taken in the caecum, transverse colon and rectum during pancolonoscopy. Microbiological culture, isolation and identification of bacteria followed.
  • Background: Colorectal cancer (CRC) is the 3rd most common cancer worldwide and the Czech Republic has the 6th highest incidence of CRC worldwide. Large intestinal microbiota play in its etiopathogenesis important role. Bacteriocins are proteins, produced by bacteria from the Enterobacteriaceae family. The aim of our prospective study was to assess the colonization of large intestinal mucosa by Escherichia coli strains and to investigate their bacteriocin production. Methods: A total of 30 consecutive patients with colorectal adenoma, CRA (17 men, 13 women, aged 39–79, mean age 63 +/- 9), 30 patients with CRC (23 men, 7 women, aged 38–86, mean age 67 +/- 11) and 20 healthy controls (9 men, 11 women, age 23–84, mean age 55 +/- 15) were enrolled into prospective study. Mucosal biopsies were taken in the caecum, transverse colon and rectum during pancolonoscopy. Microbiological culture, isolation and identification of bacteria followed. (en)
Title
  • Escherichia coli strains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia
  • Escherichia coli strains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia (en)
skos:prefLabel
  • Escherichia coli strains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia
  • Escherichia coli strains of phylogenetic group B2 and D and bacteriocin production are associated with advanced colorectal neoplasia (en)
skos:notation
  • RIV/00216224:14110/14:00078631!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 733
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  • 14976
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  • RIV/00216224:14110/14:00078631
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  • Escherichia coli; Colicins; Bacteriocins; Colorectal adenoma; Colorectal carcinoma (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [87116017EF70]
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  • BMC Infectious Diseases
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  • 14
http://linked.open...iv/tvurceVysledku
  • Cyrany, Jiří
  • Rejchrt, Stanislav
  • Šmajs, David
  • Bures, Jan
  • Cihak, Michal
  • Forstlova, Miroslava
  • Kohoutova, Darina
  • Moravkova, Monika
  • Moravkova, Paula
issn
  • 1471-2334
number of pages
http://bibframe.org/vocab/doi
  • 10.1186/s12879-014-0733-7
http://localhost/t...ganizacniJednotka
  • 14110
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