About: Spinocelulárny karcinóm v ložisku cirkumskriptnej sklerodermie     Goto   Sponge   NotDistinct   Permalink

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Description
  • Popisujeme případ mladej pacientky, u ktorej došlo k vzniku ulcerácií na právej nohe v teréne 15 rokov trvajúcej ložiskovgj sklerodermie (LS, morfey). Podlá CT vyšetrenia a RTG bol nález zhodnotený ako osteomyelitída a pacientka bola liečená kombináciou antibiotik. Opakované histologické vyšetrenia zo spodiny vředu preukázali granulačné tkanivo, chronické zápalové změny a pseudoepiteliomatóznu hyperpláziu. Stav ale progredoval a bolo nutné pristúpiť k amputécií pod kolenom. S odstupem troch mesiacov bola diagnostikovaná metastáza spino-celulárneho karcinomu v lymfatickej uzlině v triesle. Aj napriek kombinovanému přístupu (chirurgické] liečbe, rádioterapii a systémové chemoterapii) sa tvořili ďalšie metastázy a pacientka po niekolVých mesiacoch ochoreniu podlahla. Případ bol uzatvorený ako spinocelulárny karcinom maskovaný osteomyelitídou.
  • We present a case of a young 26-year-old woman, who has been suffering from localised scle-roderma (morphea) for 15 years. Recently, a lesion on the dorsum of her right foot ulcerated. Based on a CT scan and X-ray a diagnosis of ulcerative osteomyellitis was established. The patient was treated with a combination of antibiotics. Subsequent histological examinations showed granulomatous tissue and chronic inflammatory changes on top of pseudoepitelioma-tous hyperplasia. The patient's status was deteriorating, which resulted in a limb amputation under the knee. Three months later, there was a metastasis of squamous cell carcinoma found in the patient's inguinal lymph node. In spite of combined therapy (surgery, radioterapy and systemic chemotherapy), new metastases occurred and the patient succumbed to the disease several months afterwards. The case was concluded as a squamous cell carcinoma camouf¬laged by osteomyelitis. Malignant turn of localised sclerodema is very rare. (en)
Title
  • Spinocelulárny karcinóm v ložisku cirkumskriptnej sklerodermie
  • Squamous Cell Carcinoma in Localized Scleroderma (en)
skos:prefLabel
  • Spinocelulárny karcinóm v ložisku cirkumskriptnej sklerodermie
  • Squamous Cell Carcinoma in Localized Scleroderma (en)
skos:notation
  • RIV/00216224:14110/14:00077915!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 46646
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/14:00077915
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • localized scleroderma; squamous cell carcinoma; ulcer; osteomyelitis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [E531B70B17FA]
http://linked.open...i/riv/nazevZdroje
  • Klinická onkologie
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Jedličková, Hana
  • Sláma, Ondřej
  • Vašků, Vladimír
  • Březinová, Eva
  • Ďurčanská, Veronika
  • Velecký, Lukáš
issn
  • 0862-495X
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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