About: Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

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About: Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Objective: Large artery occlusion (LAO) in patients with major stroke predicts poor revascularization by intravenous thrombolysis (IVT) and more likely results in a poor outcome. We focused on the effects of intra- arterial thrombolysis (IAT) and endovascular mechanical recanalization (EMR) as rescue therapies in major strokes refractory to IVT. Methods: A retrospective analysis of 87 patients (National Institutes of Health Stroke Scale >20), who did not respond to full-dose IVT due to LAO, was performed based on their endovascular therapy status. IAT was performed as an intraclot infusion of alteplase, and EMR was provided by the Solitaire device (TM) (Covidien, Dubin, Ireland). The recanalization and 3-month outcome rates after IAT/EMR were correlated with a group of patients who were scheduled to receive endovascular treatment but who underwent only IVT. Results: We achieved successful recanalization by IAT and EMR in 68.7% and 76.1% of patients, respectively. Objective: Large artery occlusion (LAO) in patients with major stroke predicts poor revascularization by intravenous thrombolysis (IVT) and more likely results in a poor outcome. We focused on the effects of intra- arterial thrombolysis (IAT) and endovascular mechanical recanalization (EMR) as rescue therapies in major strokes refractory to IVT. Methods: A retrospective analysis of 87 patients (National Institutes of Health Stroke Scale >20), who did not respond to full-dose IVT due to LAO, was performed based on their endovascular therapy status. IAT was performed as an intraclot infusion of alteplase, and EMR was provided by the Solitaire device (TM) (Covidien, Dubin, Ireland). The recanalization and 3-month outcome rates after IAT/EMR were correlated with a group of patients who were scheduled to receive endovascular treatment but who underwent only IVT. Results: We achieved successful recanalization by IAT and EMR in 68.7% and 76.1% of patients, respectively. (en)
Title	Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis (en)
skos:prefLabel	Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis (en)
skos:notation	RIV/00216224:14110/14:00077147!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED1.100/02/0123)
http://linked.open...iv/cisloPeriodika	1036
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Jančálek, Radim Vaníček, Jiří Bulík, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	52590
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00077147
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ACUTE ISCHEMIC-STROKE; MECHANICAL THROMBECTOMY; RECANALIZATION; VALIDATION; RETRIEVER (en)
http://linked.open.../riv/klicoveSlovo	RECANALIZATION MECHANICAL THROMBECTOMY VALIDATION ACUTE ISCHEMIC-STROKE RETRIEVER
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[105E67B2D335]
http://linked.open...i/riv/nazevZdroje	BRITISH JOURNAL OF RADIOLOGY
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	87
http://linked.open...iv/tvurceVysledku	Brichta, Jaroslav Jančálek, Radim Vaníček, Jiří Bulik, Martin
http://linked.open...ain/vavai/riv/wos	000334291900006
issn	0007-1285
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1259/bjr.20130545
http://localhost/t...ganizacniJednotka	14110

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