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  • Calprotectin represents an interesting peptide known to be involved in the pathophysiology of various inflammatory processes. Being secreted from activated neutrophils and monocytes under various conditions, it can also be found in the extracellular fluids and serve as a biomarker of ongoing inflammation, which property is currently used in the monitoring of inflammatory bowel diseases. Recent studies, however, suggest that calprotectin could serve as an important prognostic factor for cardiovascular and cardiometabolic diseases, since these are occurring on the basis of low-grade chronic inflammation. We assume that calprotectin may represent a useful marker in predicting the course of atherosclerotic process, coronary artery disease and acute coronary syndromes. Our review is focused on the importance of calprotectin in the diagnosis and prognostic stratification in the field of cardiometabolic risk.
  • Calprotectin represents an interesting peptide known to be involved in the pathophysiology of various inflammatory processes. Being secreted from activated neutrophils and monocytes under various conditions, it can also be found in the extracellular fluids and serve as a biomarker of ongoing inflammation, which property is currently used in the monitoring of inflammatory bowel diseases. Recent studies, however, suggest that calprotectin could serve as an important prognostic factor for cardiovascular and cardiometabolic diseases, since these are occurring on the basis of low-grade chronic inflammation. We assume that calprotectin may represent a useful marker in predicting the course of atherosclerotic process, coronary artery disease and acute coronary syndromes. Our review is focused on the importance of calprotectin in the diagnosis and prognostic stratification in the field of cardiometabolic risk. (en)
Title
  • Role of calprotectin in cardiometabolic diseases
  • Role of calprotectin in cardiometabolic diseases (en)
skos:prefLabel
  • Role of calprotectin in cardiometabolic diseases
  • Role of calprotectin in cardiometabolic diseases (en)
skos:notation
  • RIV/00216224:14110/14:00075533!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • P(ED1.100/02/0123), S
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  • 1
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  • 43085
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  • RIV/00216224:14110/14:00075533
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  • Calprotectin; Cardiovascular diseases; Metabolic diseases; Obesity; Myocardial infarction (en)
http://linked.open.../riv/klicoveSlovo
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [EC34D0FCA7E1]
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  • Cytokine & Growth Factor Reviews
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  • 25
http://linked.open...iv/tvurceVysledku
  • Novák, Jan
  • Novák, Miroslav
  • Kružliak, Peter
  • Fodor, George J.
http://linked.open...ain/vavai/riv/wos
  • 000334082800006
issn
  • 1359-6101
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.cytogfr.2014.01.005
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  • 14110
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