About: Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children

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About: Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Introduction: Dental caries and periodontal diseases are complex, multifactorial diseases and one of the most common illnesses worldwide. Recent evidence suggests a role of LTF in caries and periodontitis. The aim of this study was determine the frequency of the polymorphism 140A/G in lactotransferrin gene and its association with dental caries and gingivitis in children in Czech population. Material and Methods: School children aged 11 – 13 years were included in the study (N = 637). The subjects were divided into two groups: without caries (DMFT = 0) and with caries (DMFT1). The caries affected group was stratified as low (DMFT=1), moderate (2DMFT3) and high (DMFT4) caries experience. The level of gingivitis was rated according to gingival index (GI) and subjects were divided into the groups without (GI = 0) and with (GI1) gingivitis. The LTF rs1126478 (140A/G exon 2, Lys/Arg) genotypes were determined by polymerase-chain reaction (PCR) with restriction analysis by EarI enzyme. Introduction: Dental caries and periodontal diseases are complex, multifactorial diseases and one of the most common illnesses worldwide. Recent evidence suggests a role of LTF in caries and periodontitis. The aim of this study was determine the frequency of the polymorphism 140A/G in lactotransferrin gene and its association with dental caries and gingivitis in children in Czech population. Material and Methods: School children aged 11 – 13 years were included in the study (N = 637). The subjects were divided into two groups: without caries (DMFT = 0) and with caries (DMFT1). The caries affected group was stratified as low (DMFT=1), moderate (2DMFT3) and high (DMFT4) caries experience. The level of gingivitis was rated according to gingival index (GI) and subjects were divided into the groups without (GI = 0) and with (GI1) gingivitis. The LTF rs1126478 (140A/G exon 2, Lys/Arg) genotypes were determined by polymerase-chain reaction (PCR) with restriction analysis by EarI enzyme. (en)
Title	Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children (en) Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children
skos:prefLabel	Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children (en) Polymorphism 140A/G in lactotransferrin gene and its association with development of dental caries and gingivitis in children
skos:notation	RIV/00216224:14110/14:00074103!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GB14-37368G), P(NT11405), S
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Izakovičová-Hollá, Lydie Kukla, Lubomír Bořilová Linhartová, Petra Kukletová, Martina Musilová, Kristína Bartošová, Michaela
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	37436
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00074103
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lactotransferrin; polymorphism; dental caries; gingivitis; children (en)
http://linked.open.../riv/klicoveSlovo	lactotransferrin gingivitis children polymorphism dental caries
http://linked.open...ontrolniKodProRIV	[FB3045B68ACE]
http://linked.open...in/vavai/riv/obor	FF
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Microbiologic and genetic determinants of the onset and progression of periodontitis in type 1 and 2 diabetics and their reciprocal relationship to diabetes compensation Centre of orofacial development and regeneration
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Izakovičová-Hollá, Lydie Kukla, Lubomír Kukletová, Martina Musilová, Kristína Bartošová, Michaela Bořilová Linhartová, Petra Trefná, Tereza Vlažný, Jan
http://localhost/t...ganizacniJednotka	14110

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