About: Arrhythmogenesis in Brugada syndrome: Impact and constrains of current concepts

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Brugada syndrome (BrS), an inherited arrhythmogenic disease first described in 1992, is characterized by ST segment elevations on the electrocardiogram in the right precordium and by a high occurrence of arrhythmias including the life-threatening ventricular tachycardia/fibrillation. Knowledge of the underlying mechanisms of formation of arrhythmogenic substrate in BrS is essential, namely for the risk stratification of BrS patients and their therapy which is still restrained almost exclusively to the implantation of cardioverter/defibrillator. In spite of many crucial findings in this field published within recent years, the final consistent view has not been established so far. Hence, BrS described 20 years ago remains an actual topic of both clinical and experimental studies. Brugada syndrome (BrS), an inherited arrhythmogenic disease first described in 1992, is characterized by ST segment elevations on the electrocardiogram in the right precordium and by a high occurrence of arrhythmias including the life-threatening ventricular tachycardia/fibrillation. Knowledge of the underlying mechanisms of formation of arrhythmogenic substrate in BrS is essential, namely for the risk stratification of BrS patients and their therapy which is still restrained almost exclusively to the implantation of cardioverter/defibrillator. In spite of many crucial findings in this field published within recent years, the final consistent view has not been established so far. Hence, BrS described 20 years ago remains an actual topic of both clinical and experimental studies. (en)
Title	Arrhythmogenesis in Brugada syndrome: Impact and constrains of current concepts Arrhythmogenesis in Brugada syndrome: Impact and constrains of current concepts (en)
skos:prefLabel	Arrhythmogenesis in Brugada syndrome: Impact and constrains of current concepts Arrhythmogenesis in Brugada syndrome: Impact and constrains of current concepts (en)
skos:notation	RIV/00216224:14110/13:00069377!RIV14-MSM-14110___
http://linked.open...avai/predkladatel	Lékařská fakulta
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622402)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Bébarová, Markéta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	62098
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/13:00069377
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Arrhythmogenesis; Atrial fibrillation; Brugada syndrome; Discontinuous conduction; Dysfunction; Mutation (en)
http://linked.open.../riv/klicoveSlovo	Arrhythmogenesis Discontinuous conduction Dysfunction Atrial fibrillation Brugada syndrome Mutation
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[761410D05C8B]
http://linked.open...i/riv/nazevZdroje	International Journal of Cardiology
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	167
http://linked.open...iv/tvurceVysledku	Bébarová, Markéta
http://linked.open...ain/vavai/riv/wos	000323569600029
http://linked.open...n/vavai/riv/zamer	Early diagnostics and treatment of cardiovascular diseases
issn	0167-5273
number of pages	12 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ijcard.2012.12.019
http://localhost/t...ganizacniJednotka	14110

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