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  • The involvement of the subthalamic nucleus (STN) in a broad spectrum of various non-motor functions – attention, executive functions, verbal learning and memory, verbal abstract reasoning, conflict resolution, and emotions – has been reported. The STN has an anatomically central position within the basal ganglia(BG)-thalamocortical motor, associative and limbic circuits. The STN might interfere with non-motor functions as an indirect modulator rather than a regulator. Mechanisms modulating the motor and non-motor functions might differ. The STN has been implicated in control of non-motor behaviors via the tuning of specific circuits depending on the task. The STN might modulate selected non-motor functions via contextual modulation of certain cortical areas. Based on intracerebral recordings, we proposed that the non-motor activities in the BG are organized in some way other than the well-known organization of the cortico-BG-thalamocortical circuits.
  • The involvement of the subthalamic nucleus (STN) in a broad spectrum of various non-motor functions – attention, executive functions, verbal learning and memory, verbal abstract reasoning, conflict resolution, and emotions – has been reported. The STN has an anatomically central position within the basal ganglia(BG)-thalamocortical motor, associative and limbic circuits. The STN might interfere with non-motor functions as an indirect modulator rather than a regulator. Mechanisms modulating the motor and non-motor functions might differ. The STN has been implicated in control of non-motor behaviors via the tuning of specific circuits depending on the task. The STN might modulate selected non-motor functions via contextual modulation of certain cortical areas. Based on intracerebral recordings, we proposed that the non-motor activities in the BG are organized in some way other than the well-known organization of the cortico-BG-thalamocortical circuits. (en)
Title
  • Involvement of the subthalamic nucleus in cognitive functions — A concept
  • Involvement of the subthalamic nucleus in cognitive functions — A concept (en)
skos:prefLabel
  • Involvement of the subthalamic nucleus in cognitive functions — A concept
  • Involvement of the subthalamic nucleus in cognitive functions — A concept (en)
skos:notation
  • RIV/00216224:14110/11:00053200!RIV12-MSM-14110___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • V
http://linked.open...iv/cisloPeriodika
  • 1-2
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  • 205774
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/11:00053200
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  • Subthalamic nucleus; Basal ganglia; Cognitive functions; Deep brain stimulation; Hyperdirect pathway (en)
http://linked.open.../riv/klicoveSlovo
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  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [D865ECF88E92]
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  • Journal of the Neurological Sciences
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http://linked.open...v/svazekPeriodika
  • 310
http://linked.open...iv/tvurceVysledku
  • Baláž, Marek
  • Rektorová, Irena
  • Rektor, Ivan
  • Bočková, Martina
http://linked.open...ain/vavai/riv/wos
  • 000296927500024
issn
  • 0022-510X
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.jns.2011.07.016
http://localhost/t...ganizacniJednotka
  • 14110
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