About: Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917     Goto   Sponge   NotDistinct   Permalink

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  • AIM: To evaluate bacteriocinogeny in short-term high-dose indomethacin administration with or without probiotic Escherichia coli Nissle 1917 (EcN) in experimental pigs. METHODS: Twenty-four pigs entered the study: Group A (controls), Group B (probiotics alone), Group C (indomethacin alone) and Group D (probiotics and indomethacin). EcN (3.5x1010 bacteria/d for 14 d) and/or indomethacin (15 mg/kg per day for 10 d) were administrated orally. Anal smears before and smears from the small and large intestine were taken from all animals. Bacteriocin production was determined with 6 different indicator strains. RESULTS: The general microbiota profile was rather uniform in all animals but there was a broad diversity in coliform bacteria (parallel genotypes A, B1, B2 and D found). CONCLUSION: EcN did not exert long-term liveability in the porcine intestine. All experimental pigs remained methanogenic. Indomethacin and EcN administered together might produce the worst impact on bacteriocinogeny.
  • AIM: To evaluate bacteriocinogeny in short-term high-dose indomethacin administration with or without probiotic Escherichia coli Nissle 1917 (EcN) in experimental pigs. METHODS: Twenty-four pigs entered the study: Group A (controls), Group B (probiotics alone), Group C (indomethacin alone) and Group D (probiotics and indomethacin). EcN (3.5x1010 bacteria/d for 14 d) and/or indomethacin (15 mg/kg per day for 10 d) were administrated orally. Anal smears before and smears from the small and large intestine were taken from all animals. Bacteriocin production was determined with 6 different indicator strains. RESULTS: The general microbiota profile was rather uniform in all animals but there was a broad diversity in coliform bacteria (parallel genotypes A, B1, B2 and D found). CONCLUSION: EcN did not exert long-term liveability in the porcine intestine. All experimental pigs remained methanogenic. Indomethacin and EcN administered together might produce the worst impact on bacteriocinogeny. (en)
Title
  • Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917
  • Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917 (en)
skos:prefLabel
  • Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917
  • Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917 (en)
skos:notation
  • RIV/00216224:14110/11:00051585!RIV12-MZ0-14110___
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  • I, P(NS9665), Z(MSM0021622415), Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika
  • 5
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  • 187752
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  • RIV/00216224:14110/11:00051585
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  • Bacteriocinogeny; Escherichia coli Nissle 1917; Experimental pigs; Indomethacin (en)
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  • CN - Čínská lidová republika
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  • [84AE270800DE]
http://linked.open...i/riv/nazevZdroje
  • Wourld Journal of Gastroenterology
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  • 17
http://linked.open...iv/tvurceVysledku
  • Bureš, Jan
  • Cyrany, Jiří
  • Főrstl, Miroslav
  • Kuneš, Martin
  • Květina, Jaroslav
  • Kopáčová, Marcela
  • Kohoutová, Darina
  • Lesná, Jiřina
  • Rejchrt, Stanislav
  • Tachecí, Ilja
  • Voříšek, Viktor
  • Šmarda, Jan
  • Šmajs, David
http://linked.open...ain/vavai/riv/wos
  • 000287627700008
http://linked.open...n/vavai/riv/zamer
issn
  • 1007-9327
number of pages
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  • 10.3748/wjg.v17.i5.609
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  • 14110
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