About: Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome

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About: Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Though pathophysiology of PHH is more complicated and TGF-beta1 is not the only one to play a role in it, we have documented in our study that TGF-beta1 level in CSF collected in the beginning of temporary treatment of PHH correlates with failure of CSF resorption. In our study, in 62.5% of patients with proof of obstruction, hyporesorptive component was present. Overall, ETV success rate in therapy of obstructive PHH 37.5% in our study. We have proven that premature newborns with lower TGF-beta1 level and proof of obstructive HDC on MRI have significantly higer success rate of endoscopic treatment. In our study, ETV success rate was 100% in this group. Our results show that TGF-beta1 may influence succes rate of ETV in treatment of PHH, and based on its levels, it is possible to choose patients with purely obstructive hydrocephalus. Though pathophysiology of PHH is more complicated and TGF-beta1 is not the only one to play a role in it, we have documented in our study that TGF-beta1 level in CSF collected in the beginning of temporary treatment of PHH correlates with failure of CSF resorption. In our study, in 62.5% of patients with proof of obstruction, hyporesorptive component was present. Overall, ETV success rate in therapy of obstructive PHH 37.5% in our study. We have proven that premature newborns with lower TGF-beta1 level and proof of obstructive HDC on MRI have significantly higer success rate of endoscopic treatment. In our study, ETV success rate was 100% in this group. Our results show that TGF-beta1 may influence succes rate of ETV in treatment of PHH, and based on its levels, it is possible to choose patients with purely obstructive hydrocephalus. (en)
Title	Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome (en)
skos:prefLabel	Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome (en)
skos:notation	RIV/00216224:14110/10:00047019!RIV11-MSM-14110___
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Brichtová, Eva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	284616
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/10:00047019
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Posthemorrhagic hydrocephalus Endoscopic third ventriculostomy Transforming growth factor beta1 Premature infants (en)
http://linked.open.../riv/klicoveSlovo	Posthemorrhagic hydrocephalus Endoscopic third ventriculostomy Transforming growth factor beta1 Premature infants
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[BD145B5A07A1]
http://linked.open...i/riv/nazevZdroje	Childs Nerv Syst
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	26
http://linked.open...iv/tvurceVysledku	Nováčková, Ludmila Lipina, Radim Reguli, Štefan Brichtová, Eva Podešvová, Hana
issn	0256-7040
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome Relation between TGF-beta1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus. Relation between TGF-ß1 levels in cerebrospinal fluid and ETV outcome

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