About: Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate

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About: Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The new original method for assessment the metabolic activity of both rat CYP1A2 and CYP2C6/11 is presented in the paper. The method of simultaneous determination of phenacetin, tolbutamide and their metabolites is rapid simple, repeatable and precious and sensitive enough for pharmacokinetic studies. The new original method for assessment the metabolic activity of both rat CYP1A2 and CYP2C6/11 is presented in the paper. The method of simultaneous determination of phenacetin, tolbutamide and their metabolites is rapid simple, repeatable and precious and sensitive enough for pharmacokinetic studies. (en)
Title	Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate (en)
skos:prefLabel	Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate (en)
skos:notation	RIV/00216224:14110/10:00043518!RIV11-GA0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP206/10/0057), P(LC06023), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Juřica, Jan Tomandl, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	287517
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/10:00043518
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CYP2C6; CYP1A2; metabolic activity; marker (en)
http://linked.open.../riv/klicoveSlovo	CYP1A2 CYP2C6 marker metabolic activity
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D839C7DDDBCA]
http://linked.open...i/riv/nazevZdroje	Journal of Pharmaceutical and Biomedical Analysis
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Integrated bioanalytical technologies for microanalyses and diagnostics with laser induced fluorescence and mass spectrometry coupling. Miniaturised on-line drug-metabolism system based on capillary electrophoresis
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Juřica, Jan Tomandl, Josef Zahradníková, Lucia Konečný, Jiří
http://linked.open...ain/vavai/riv/wos	000276057300017
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	0731-7085
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate

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