About: ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We evaluated the associations among angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism, ACE activity and post-myocardial infarction left ventricular dysfunction and acute heart failure early after presentation with MI with ST-segment elevation. A total of 556 patients with STEMI treated by primary PCI were the study population. The DD/ID genotypes were associated with a significantly higher risk of EF. These results suggest that the I/D polymorphism of ACE is associated with the development of LV dysfunction in the acute phase after STEMI. We demonstrated for the first time an association of the low ACE activity with the severe LV dysfunction, although patients with moderate LV dysfunction had higher level ACE activity than patients with preserved LV function. We evaluated the associations among angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism, ACE activity and post-myocardial infarction left ventricular dysfunction and acute heart failure early after presentation with MI with ST-segment elevation. A total of 556 patients with STEMI treated by primary PCI were the study population. The DD/ID genotypes were associated with a significantly higher risk of EF. These results suggest that the I/D polymorphism of ACE is associated with the development of LV dysfunction in the acute phase after STEMI. We demonstrated for the first time an association of the low ACE activity with the severe LV dysfunction, although patients with moderate LV dysfunction had higher level ACE activity than patients with preserved LV function. (en)
Title	ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI (en)
skos:prefLabel	ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI (en)
skos:notation	RIV/00216224:14110/10:00040848!RIV11-MZ0-14110___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NS9880)
http://linked.open...iv/cisloPeriodika	60
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Prymusová, Krystyna Tesák, Martin Pařenica, Jiří Tomandl, Josef Kala, Petr Maňoušek, Jan Kubková, Lenka Vašků, Anna Poloczek, Martin Toman, Ondřej Špinar, Jindřich Jarkovský, Jiří Pávková Goldbergová, Monika
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	245214
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/10:00040848
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ACE; polymorphism; gene; myocardial infarction (en)
http://linked.open.../riv/klicoveSlovo	gene polymorphism myocardial infarction ACE
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B3EA30D42762]
http://linked.open...i/riv/nazevZdroje	BMC Cardiovascular Disorders
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	13 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Mnagment of care of patients with acute heart failure, their min-term prognosis and multivariate prognostic model.
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	10
http://linked.open...iv/tvurceVysledku	Jarkovský, Jiří Kala, Petr Kubková, Lenka Maňoušek, Jan Pařenica, Jiří Poloczek, Martin Tesák, Martin Toman, Ondřej Tomandl, Josef Vašků, Anna Špinar, Jindřich Pávková Goldbergová, Monika Prymusová, Krystyna Tomčíková, D.
issn	1471-2261
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI ACE gene insertion/deletion polymorphism has a moderate influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 35 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software