About: Etiology of small-fiber neuropathy

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim was to evaluate the etiology in a group of 84 patients with painful sensory neuropathy with predominant small-fiber dysfunction(54 men,30 women,median:58; range:25-83 years).Involvement of small nerve fibers was verified by abnormal thermal thresholds and/or reduced intraepidermal nerve fiber densities.Motor signs or symptoms or significant clinical signs of sensory large-fiber involvement were exclusionary;33 patients,however,had sensory nerve conduction abnormalities.The multivariate regression model disclosed that diabetes mellitus(odds ratio [OR]=4.08),chronic alcoholism(OR=5.31),and serum cholesterol levels(OR=4.51)were the only parameters independently associated with small-fiber involvement.No possible etiology was detected in 19 patients(22.6%).In conclusion,the spectrum of risk factors and proportion of idiopathic cases in geographically defined small-fiber polyneuropathy sample is similar to that referred in large-fiber polyneuropathy. The aim was to evaluate the etiology in a group of 84 patients with painful sensory neuropathy with predominant small-fiber dysfunction(54 men,30 women,median:58; range:25-83 years).Involvement of small nerve fibers was verified by abnormal thermal thresholds and/or reduced intraepidermal nerve fiber densities.Motor signs or symptoms or significant clinical signs of sensory large-fiber involvement were exclusionary;33 patients,however,had sensory nerve conduction abnormalities.The multivariate regression model disclosed that diabetes mellitus(odds ratio [OR]=4.08),chronic alcoholism(OR=5.31),and serum cholesterol levels(OR=4.51)were the only parameters independently associated with small-fiber involvement.No possible etiology was detected in 19 patients(22.6%).In conclusion,the spectrum of risk factors and proportion of idiopathic cases in geographically defined small-fiber polyneuropathy sample is similar to that referred in large-fiber polyneuropathy. (en)
Title	Etiology of small-fiber neuropathy Etiology of small-fiber neuropathy (en)
skos:prefLabel	Etiology of small-fiber neuropathy Etiology of small-fiber neuropathy (en)
skos:notation	RIV/00216224:14110/09:00038063!RIV11-MZ0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NS9667), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Bednařík, Josef Dušek, Ladislav Moravcová, Eva Divišová, Šárka Bělobrádková, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	313665
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/09:00038063
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	etiology; painful sensory neuropathy; risk factors; small-fiber neuropathy (en)
http://linked.open.../riv/klicoveSlovo	risk factors etiology small-fiber neuropathy painful sensory neuropathy
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E8F5A03A7FDD]
http://linked.open...i/riv/nazevZdroje	Journal of the Peripheral Nervous System
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Painful diabetic neuropathy
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	14
http://linked.open...iv/tvurceVysledku	Bednařík, Josef Dušek, Ladislav Vlčková, Eva Bělobrádková, Jana Buršová, Šárka Sommer, Claudia
http://linked.open...ain/vavai/riv/wos	000271639200004
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	1085-9489
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Etiology of small-fiber neuropathy Etiology of small-fiber neuropathy Etiology of small-fiber neuropathy

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