About: Small-fibre involvement in diabetic patients with neuropathic foot pain

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To assess small-fiber involvement in diabetic patients with neuropathic pain. Methods: Peripheral nerve function was evaluated in a cohort of 30 patients with diabetes mellitus type 2 (DM2, 24 patients) or impaired glucose tolerance (IGT, 6 cases), and clinical symptoms of neuropathic pain in the feet, using nerve conduction studies, autonomic tests, thermal quantitative sensory testing (T-QST) and the quantification of intra and subepidermal nerve fiber densities in skin punch biopsies. Results: Clinical signs of isolated small-fiber sensory involvement were present in 13 patients (pure small-fiber neuropathy pSFN), 7 patients had isolated positive sensory symptoms without neurological deficits (pSFN). Ten patients had concomitant electrophysiological and/or clinical signs of large-fiber sensory involvement (mixed-fiber neuropathy MFN). Twenty seven patients (90%) had both reduced skin innervation and abnormalities of the T-QST parameters. To assess small-fiber involvement in diabetic patients with neuropathic pain. Methods: Peripheral nerve function was evaluated in a cohort of 30 patients with diabetes mellitus type 2 (DM2, 24 patients) or impaired glucose tolerance (IGT, 6 cases), and clinical symptoms of neuropathic pain in the feet, using nerve conduction studies, autonomic tests, thermal quantitative sensory testing (T-QST) and the quantification of intra and subepidermal nerve fiber densities in skin punch biopsies. Results: Clinical signs of isolated small-fiber sensory involvement were present in 13 patients (pure small-fiber neuropathy pSFN), 7 patients had isolated positive sensory symptoms without neurological deficits (pSFN). Ten patients had concomitant electrophysiological and/or clinical signs of large-fiber sensory involvement (mixed-fiber neuropathy MFN). Twenty seven patients (90%) had both reduced skin innervation and abnormalities of the T-QST parameters. (en)
Title	Small-fibre involvement in diabetic patients with neuropathic foot pain Small-fibre involvement in diabetic patients with neuropathic foot pain (en)
skos:prefLabel	Small-fibre involvement in diabetic patients with neuropathic foot pain Small-fibre involvement in diabetic patients with neuropathic foot pain (en)
skos:notation	RIV/00216224:14110/08:00051171!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita	I V Z
http://linked.open...avai/riv/aktivity	I, V, Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Bednařík, Josef Moravcová, Eva Bělobrádková, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	395379
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/08:00051171
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	diabetic neuropathy; pain; skin biopsy; small-fibre; thermal threshold (en)
http://linked.open.../riv/klicoveSlovo	pain diabetic neuropathy small-fibre thermal threshold skin biopsy
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[F9CEDE9AE3E3]
http://linked.open...i/riv/nazevZdroje	Diabetic Medicine
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Bednařík, Josef Vlčková, Eva Bělobrádková, Jana Sommer, C.
http://linked.open...ain/vavai/riv/wos	000256376400009
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	0742-3071
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1464-5491.2008.02446.x
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Small-fibre involvement in diabetic patients with neuropathic foot pain Small-fibre involvement in diabetic patients with neuropathic foot pain

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