About: Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aim: The pathophysiology of pre-eclampsia, one of the leading causes of maternal mortality worldwide, still remains unclear. Recently, it has been suggested that impaired regulation of complex interactions among various adipokines plays an important role in the development of pre-eclampsia. The aim of this study was to investigate whether the two common polymorphisms of the leptin (LEP) and adiponectin (APM1) genes are associated with the development of pre-eclampsia and its related traits (gestational hypertension, proteinuria and various measures of reduced fetal growth) in the Czech pre-eclamptic population. Methods: The case-control study comprised a total of 123 pre-eclamptic women and 150 healthy controls of similar age and parity distribution. They were genotyped for the LEP -2548G/A (5-untranslated region) and APM1 T94G (exon 2) polymorphisms using polymerase chain reaction. Results: The allele frequency of the LEP -2548G polymorphism was 0.541 in the pre-eclamptic group versus 0. Aim: The pathophysiology of pre-eclampsia, one of the leading causes of maternal mortality worldwide, still remains unclear. Recently, it has been suggested that impaired regulation of complex interactions among various adipokines plays an important role in the development of pre-eclampsia. The aim of this study was to investigate whether the two common polymorphisms of the leptin (LEP) and adiponectin (APM1) genes are associated with the development of pre-eclampsia and its related traits (gestational hypertension, proteinuria and various measures of reduced fetal growth) in the Czech pre-eclamptic population. Methods: The case-control study comprised a total of 123 pre-eclamptic women and 150 healthy controls of similar age and parity distribution. They were genotyped for the LEP -2548G/A (5-untranslated region) and APM1 T94G (exon 2) polymorphisms using polymerase chain reaction. Results: The allele frequency of the LEP -2548G polymorphism was 0.541 in the pre-eclamptic group versus 0. (en)
Title	Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? (en)
skos:prefLabel	Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? (en)
skos:notation	RIV/00216224:14110/08:00033484!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	V
http://linked.open...avai/riv/aktivity	V
http://linked.open...iv/cisloPeriodika	XX
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bienert, Petr Vašků, Anna Bienertová-Vašků, Julie Dostálová, Zuzana Unzeitig, Vít Kaňková, Kateřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	373362
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/08:00033484
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adiponectin; leptin; polymorphism; preeclampsia (en)
http://linked.open.../riv/klicoveSlovo	polymorphism adiponectin leptin preeclampsia
http://linked.open...odStatuVydavatele	JP - Japonsko
http://linked.open...ontrolniKodProRIV	[C237C8818B80]
http://linked.open...i/riv/nazevZdroje	The Journal of Obstetrics and Gynaecology Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	2008
http://linked.open...iv/tvurceVysledku	Bienertová Vašků, Julie Bienert, Petr Dostálová, Zuzana Unzeitig, Vít Vašků, Anna Kaňková, Kateřina
http://linked.open...ain/vavai/riv/wos	000259270800014
issn	1341-8076
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes? Is there any link between severe pre-eclampsia and defined polymorphisms in leptin and adiponectin genes?

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 112 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software