About: Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Objective To evaluate the clinical status and radiographic progression in patients with rheamzatoid arthritis (RA) being followed by the Czech National Registry of biological treatments. Methods Patients who failed at least two disease-modifying antirheumatic drugs and had high disease activity (DAS28 > 5.1) were treated with infliximab. Radiographic progression was measured with a modified version of the Sharp score (TSS) after 54 weeks of treatment. Results Ninety-nine patients with an average disease duration of 13.7 years were enrolled. The DAS28 dropped from 6.66 to 4.07 (p < 0.001). Before treatment the mean TSS was 90.1 and the mean estimated yearly disease progression was 8.56. After 54 weeks of infliximab, radiographic progression was 4.15 times slower than the estimated rate before treatment and 63 patients did not show any radiographic progression at all. In the remaining 36 patients, the progression rate slowed to 3.8 +/- 0.9 from the estimated TSS of 10.9 +/- 6. Objective To evaluate the clinical status and radiographic progression in patients with rheamzatoid arthritis (RA) being followed by the Czech National Registry of biological treatments. Methods Patients who failed at least two disease-modifying antirheumatic drugs and had high disease activity (DAS28 > 5.1) were treated with infliximab. Radiographic progression was measured with a modified version of the Sharp score (TSS) after 54 weeks of treatment. Results Ninety-nine patients with an average disease duration of 13.7 years were enrolled. The DAS28 dropped from 6.66 to 4.07 (p < 0.001). Before treatment the mean TSS was 90.1 and the mean estimated yearly disease progression was 8.56. After 54 weeks of infliximab, radiographic progression was 4.15 times slower than the estimated rate before treatment and 63 patients did not show any radiographic progression at all. In the remaining 36 patients, the progression rate slowed to 3.8 +/- 0.9 from the estimated TSS of 10.9 +/- 6. (en)
Title	Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment (en)
skos:prefLabel	Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment (en)
skos:notation	RIV/00216224:14110/07:00033158!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(1M0571)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Dušek, Ladislav Svobodník, Adam
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	446316
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/07:00033158
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	rheumatoid arthritis; biological treatment; radiographic progression (en)
http://linked.open.../riv/klicoveSlovo	radiographic progression rheumatoid arthritis biological treatment
http://linked.open...odStatuVydavatele	IT - Italská republika
http://linked.open...ontrolniKodProRIV	[3AEB5F44E7CA]
http://linked.open...i/riv/nazevZdroje	Clinical and Experimental Rheumatology
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Bioindication and revitalization of toxic and antropogenic substrates and water sources: application of cyano bacteria, algae, soil bacteria and symbiotic fungi
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	25
http://linked.open...iv/tvurceVysledku	Dušek, Ladislav Svobodník, Adam Pavelka, K. Gatterova, J. Jarosova, K. Studynkova, J. T. Svihalek, J. Tegzova, D. Vencovsky, J.
issn	0392-856X
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment Radiographic progression of rheumatoid arthritis in patients from the Czech National Registry receiving infiiximab treatment

Faceted Search & Find service v1.16.116 as of Feb 22 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of Feb 22 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 80 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software