About: Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease.     Goto   Sponge   NotDistinct   Permalink

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Description
  • Parkinson's disease (PD) affects speech, including respiration, phonation, and articulation. We measured the BOLD response to overt sentence reading in: 9 treated female patients with mild to moderate PD and 8 age-matched healthy female controls. Speech was recorded in the scanner to assess which brain regions underlie variations in the initiation and paralinguistic aspects of speech production. In PD patients, as compared with controls, we found significantly higher BOLD signal in the right primary orofacial sensorimotor cortex and more robust correlations between the measured speech parameters and the BOLD response to reading, particularly, in the left primary orofacial sensorimotor cortex.
  • Parkinson's disease (PD) affects speech, including respiration, phonation, and articulation. We measured the BOLD response to overt sentence reading in: 9 treated female patients with mild to moderate PD and 8 age-matched healthy female controls. Speech was recorded in the scanner to assess which brain regions underlie variations in the initiation and paralinguistic aspects of speech production. In PD patients, as compared with controls, we found significantly higher BOLD signal in the right primary orofacial sensorimotor cortex and more robust correlations between the measured speech parameters and the BOLD response to reading, particularly, in the left primary orofacial sensorimotor cortex. (en)
Title
  • Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease.
  • Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease. (en)
skos:prefLabel
  • Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease.
  • Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease. (en)
skos:notation
  • RIV/00216224:14110/07:00023382!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622404)
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  • 14
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 422716
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/07:00023382
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • overt reading; paralinguistic aspects of speech; Parkinson's disease; functional magnetic resonance imaging (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [39E1ADC48E01]
http://linked.open...i/riv/nazevZdroje
  • Movement Disorders
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 22
http://linked.open...iv/tvurceVysledku
  • Rektorová, Irena
  • Rektor, Ivan
  • Mikl, Michal
  • Paus, Tomáš
  • Barrett, Jane
http://linked.open...ain/vavai/riv/wos
  • 000250697300006
http://linked.open...n/vavai/riv/zamer
issn
  • 0885-3185
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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