About: fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.     Goto   Sponge   NotDistinct   Permalink

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  • There is extensive variance in the Laterality index (LI) calculation across the studies, and the optimal calculation method remains unclear. We attempted to calculate the LI in different ways in the same subjects, in order to find the LI calculation method with the highest correlation to the Wada test. Regions of interest (ROIs), with a known association with language function were defined. First, the LIs were calculated from the ROIs using a previously reported method (simple suprathreshold count). Next, we used several new methods of LI calculation (t-weighting of voxels, methods independent of the choice of the statistical threshold, etc.) The most significant correlation with Wada was proven in the LIs that were evaluated from Broca's area. However, the new LI calculation methods used in the present study did not produce a statistically significant benefit in comparison to previously reported methods.
  • There is extensive variance in the Laterality index (LI) calculation across the studies, and the optimal calculation method remains unclear. We attempted to calculate the LI in different ways in the same subjects, in order to find the LI calculation method with the highest correlation to the Wada test. Regions of interest (ROIs), with a known association with language function were defined. First, the LIs were calculated from the ROIs using a previously reported method (simple suprathreshold count). Next, we used several new methods of LI calculation (t-weighting of voxels, methods independent of the choice of the statistical threshold, etc.) The most significant correlation with Wada was proven in the LIs that were evaluated from Broca's area. However, the new LI calculation methods used in the present study did not produce a statistically significant benefit in comparison to previously reported methods. (en)
Title
  • fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.
  • fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation. (en)
skos:prefLabel
  • fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.
  • fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation. (en)
skos:notation
  • RIV/00216224:14110/07:00023352!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 422276
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/07:00023352
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Language; Laterality index; Temporal lobe epilepsy; fMRI; Wada test (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [65F308DCB58F]
http://linked.open...i/riv/nazevZdroje
  • Experimental Brain Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 179
http://linked.open...iv/tvurceVysledku
  • Rektor, Ivan
  • Brázdil, Milan
  • Mikl, Michal
  • Krupa, Petr
  • Pažourková, Marta
  • Chlebus, Pavel
http://linked.open...ain/vavai/riv/wos
  • 000246225000003
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-4819
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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